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Patient factors associated with embolization or splenectomy within 30 days of initiating surveillance for splenic trauma

dc.rights.licenseopenen_US
hal.structure.identifierCentre Hospitalier Universitaire [CHU Grenoble] [CHUGA]
dc.contributor.authorTIDADINI, Fatah
hal.structure.identifierAix-Marseille Université - École de médecine [AMU SMPM MED]
dc.contributor.authorMARTINET, Eugenie
hal.structure.identifiercentre d’investigation clinique de Grenoble INSERM [CIC-INSERM 1406 Grenoble]
dc.contributor.authorQUESADA, Jean-Louis
hal.structure.identifierLife Science Analytics Elsevier
hal.structure.identifierCentre Hospitalier Universitaire [CHU Grenoble] [CHUGA]
dc.contributor.authorFOOTE, Alison
dc.contributor.authorEL WAFIR, Chayma
hal.structure.identifierLaboratoire d'Anatomie des Alpes Françaises [LADAF]
hal.structure.identifierUniversité Grenoble Alpes [2016-2019] [UGA [2016-2019]]
hal.structure.identifierCentre Hospitalier Universitaire [CHU Grenoble] [CHUGA]
hal.structure.identifierIngénierie Biomédicale et Mécanique des Matériaux [TIMC-IMAG-BioMMat]
dc.contributor.authorGIRARD, Edouard
hal.structure.identifierUniversity Hospital Grenoble-Alpes, BP 217, 38043 Grenoble Cedex 9, France. 8
dc.contributor.authorARVIEUX, Catherine
hal.structure.identifierDépartement de chirurgie digestive et de l'urgence
dc.contributor.authorABBA, Julio
dc.contributor.authorAL-NAASAN, Irchid
dc.contributor.authorAARTEAGA, Charles
hal.structure.identifierUniversity Hospital Grenoble-Alpes, BP 217, 38043 Grenoble Cedex 9, France. 8
dc.contributor.authorBARBOIS, Sandrine
hal.structure.identifierLaboratoire de Biomécanique Appliquée [LBA UMR T24]
dc.contributor.authorBEGE, Thierry
dc.contributor.authorBERGI, Jean-Paul
hal.structure.identifierBiologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases
dc.contributor.authorBIAIS, Matthieu
dc.contributor.authorBOUHOURS, Guillaume
hal.structure.identifierCentre Hospitalier Universitaire d'Angers [CHU Angers]
dc.contributor.authorBOUVIER, Antoine
hal.structure.identifierModélisation et Évaluation des données complexes en Santé Publique [TIMC-MESP]
hal.structure.identifierCentre Hospitalier Universitaire [CHU Grenoble] [CHUGA]
dc.contributor.authorBOSSON, Jean-Luc
hal.structure.identifierUniv. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, [UGA, GIN]
hal.structure.identifierUniversité Grenoble Alpes [UGA]
hal.structure.identifier[GIN] Grenoble Institut des Neurosciences [GIN]
dc.contributor.authorBOUZAT, Pierre
hal.structure.identifierAssistance Publique - Hôpitaux de Marseille [APHM]
dc.contributor.authorCHAUMOITRE, Katia
hal.structure.identifierCHU Montpellier = Montpellier University Hospital
dc.contributor.authorCHARBIT, Jonathan
hal.structure.identifierMethodS in Patients-centered outcomes and HEalth ResEarch [SPHERE]
hal.structure.identifierService d'anesthésie et réanimation chirurgicale [Nantes]
hal.structure.identifierCentre Hospitalier Universitaire de Nantes = Nantes University Hospital [CHU Nantes]
dc.contributor.authorCINOTTI, Raphael
dc.contributor.authorCLUZEL, Philippe
dc.contributor.authorCOMPAGNON, Philippe
dc.contributor.authorCOTTON, François
dc.contributor.authorCOUTARD, Myriam
dc.contributor.authorDABAN, Jean Louis
dc.contributor.authorDARAGON, Charles
dc.contributor.authorDAVID, Jean-Stéphane
dc.contributor.authorDOUANE, Frederic
dc.contributor.authorDUBUISSON, Vincent
dc.contributor.authorEGO, Anne
dc.contributor.authorFERNANDEZ, Patrice
dc.contributor.authorFRANDON, Julien
dc.contributor.authorGARRIGUE, Delphine
dc.contributor.authorGUELFI, Julien
dc.contributor.authorGUILLON, Françoise
dc.contributor.authorHABERLAY, Marc
dc.contributor.authorHENTATI, Hassen
dc.contributor.authorHENRY, Christophe
dc.contributor.authorHORNEZ, Emmanuel
dc.contributor.authorKOBEITER, Hicham
dc.contributor.authorHUET, Nicolas
dc.contributor.authorLEBRAS, Yann
dc.contributor.authorLEMOINE, Marie-Christine
dc.contributor.authorLEONE, Marc
dc.contributor.authorLERMITE, Emilie
dc.contributor.authorLESAVRE, Nathalie
dc.contributor.authorLEVRAT, Albrice
dc.contributor.authorMARTINILLI, Thomas
dc.contributor.authorMEAUDRE, Eric
dc.contributor.authorMESTRALLET, Jean-Philippe
dc.contributor.authorMETAIRIE, Sylvie
dc.contributor.authorMICHOUD, Marie
dc.contributor.authorMONCHAL, Tristan
dc.contributor.authorMONNIN-BARES, Valérie
dc.contributor.authorMULLER, Laurent
dc.contributor.authorNZAMUSHE, Jean-Robert
dc.contributor.authorPASSOT, Guillaume
dc.contributor.authorPICARD, Julien
dc.contributor.authorPLENIER, Isabelle
dc.contributor.authorPRUNET, Bertrand
dc.contributor.authorRAUX, Mathieu
dc.contributor.authorRIDEREAU, Catherine
dc.contributor.authorRODIERE, Mathieu
dc.contributor.authorTERIITEHAU, Christophe
dc.contributor.authorTEREBUS-LOOCK, Melanie
dc.contributor.authorTHOURET, Jean-Marc
dc.contributor.authorTHONY, Frédéric
dc.contributor.authorTRESALLET, Christophe
dc.contributor.authorVALETTE, Pierre-Jean
dc.contributor.authorVILOTITCH, Antoine
dc.contributor.authorVOIGLIO, Eric
dc.contributor.authorALPES, Grenoble
dc.contributor.authorSUD, Lyon
dc.contributor.authorPARIS, Pitié-Salpêtrière
dc.contributor.authorCRÉTEIL, Henri-Mondor
dc.contributor.authorTOULON, Sainte-Anne
dc.date.accessioned2024-12-09T10:16:25Z
dc.date.available2024-12-09T10:16:25Z
dc.date.issued2024-10-04
dc.identifier.issn1070-3004en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/203789
dc.description.abstractEnBackground: Non-operative management of hemodynamically stable patients with splenic trauma has been recommended for more than 25 years, but in practice embolization and/or splenectomy (intervention) is often needed within the first 30 days. Identifying the risk factors associated with the need for intervention could support more individualized decision-making. Methods: We used data from the SPLASH randomized clinical trial, a comparison of outcomes of surveillance or embolization. 140 patients were randomized, 133 retained in the study (embolization n = 66; surveillance n = 67) and 103 screened and registered in the non-inclusion register. Multivariate Cox proportional hazards models with time-varying covariates were used to identify risk factors contributing to embolization and/or splenectomy within 30 days after initiating surveillance only for splenic trauma. Results: 123 patients (median age, 30 [23; 48] years; 91 (74%) male) initially received non-operative management. At the day-30 visit, 34 (27.6%) patients had undergone an intervention (31 (25.2%) delayed embolization and 4 (3.3%) splenectomy). Multivariate analysis identified patients with OIS grade 4 or 5 splenic trauma (HR = 4.51 [2.06-9.88]) and (HR = 34.5 [6.84-174]); respectively) and splenic complications: arterial leak (HR = 1.80 [1.45-2.24]), pseudoaneurysm (HR = 1.22 [1.06-1.40]) and pseudocyst (HR = 1.41 [1.21-1.64]) to be independently associated with increased risk of need for an intervention within 30 days of initiating surveillance. Conclusions: Our study shows that more than 1 in 4 patients who received non-operative management needed embolization or splenectomy by day 30. Arterial leak, pseudoaneurysm, pseudocyst, and OIS grade 4 or 5 were independent risk factors linked to the need for an intervention.
dc.language.isoENen_US
dc.subject.enEmbolization; Risk factors; Splenectomy; Splenic trauma; Surveillance
dc.title.enPatient factors associated with embolization or splenectomy within 30 days of initiating surveillance for splenic trauma
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s10140-024-02285-3en_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologieen_US
dc.identifier.pubmed39365384en_US
bordeaux.journalEmergency Radiologyen_US
bordeaux.hal.laboratoriesBiologie des maladies cardiovasculaires (BMC) - UMR 1034en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-04820220
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Emergency%20Radiology&rft.date=2024-10-04&rft.eissn=1070-3004&rft.issn=1070-3004&rft.au=TIDADINI,%20Fatah&MARTINET,%20Eugenie&QUESADA,%20Jean-Louis&FOOTE,%20Alison&EL%20WAFIR,%20Chayma&rft.genre=article


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