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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorGAYRAUD, Laure
dc.contributor.authorMORTAMAIS, Marion
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorSCHWEITZER, Cedric
ORCID: 0000-0002-2162-9479
IDREF: 133631583
dc.contributor.authorDE HOOGH, Kees
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorGREGOIRE, Audrey
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorKOROBELNIK, Jean-Francois
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDELYFER, Marie-Noelle
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorROUGIER, Marie-Benedicte
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLEFFONDRE, Karen
IDREF: 183599128
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorHELMER, Catherine
dc.contributor.authorVIENNEAU, Danielle
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDELCOURT, Cecile
dc.date.accessioned2024-11-27T09:05:38Z
dc.date.available2024-11-27T09:05:38Z
dc.date.issued2024-11-11
dc.identifier.issn1755-3768en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/203497
dc.description.abstractEnCataract, the leading cause of blindness worldwide, is a multifactorial disease involving oxidative stress mechanisms. The aim of our study was to investigate the relationship between air pollution exposure and the incidence of cataract surgery. The 3C-Alienor study is a population-based cohort of residents of Bordeaux, France, aged 65 years or more, recruited in 1999-2000 and followed every 2-3 years until 2017. Cataract surgery was self-reported and checked at slit-lamp by trained professionals. Average air pollution exposure (particulate matter ≤2.5 μm (PM), black carbon (BC), nitrogen dioxide (NO)) in the 10 years preceding baseline was estimated at the participants' geocoded residential address, using temporally adjusted land use regression. Associations of 10-year average air pollution exposure with incidence of cataract were estimated using Cox proportional hazard models adjusted for confounders. The study included 829 subjects without cataract surgery prior to inclusion; the mean age at inclusion was 72.6 years (standard deviation (SD): 4.2) and 61% were women. The median (Interquartile-range (IQR)) follow-up duration was 14.1 (6.4) years during which 507 participants underwent cataract surgery. Exposure to a concentration ≥40 μg/m of NO (the current regulatory limit value in Europe) was associated with incident cataract surgery (HR = 1.46, CI (1.16, 1.84), p = 0.001). No statistically significant association was found with PM and BC. Long-term exposure to a NO concentration ≥ 40 μg/m was associated with an increased incidence of cataract surgery. Complying with current European air pollution standards could reduce cataract surgery costs and improve population quality of life.
dc.description.sponsorship/ - ANR-10-PRSP-0011en_US
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enNO2
dc.subject.enAir Pollution
dc.subject.enCataract
dc.subject.enEye Disease
dc.subject.enFine Particulate Matter
dc.subject.enOxidative Stress
dc.title.enAmbient air pollution exposure and incidence of cataract surgery: The prospective 3City-Alienor study
dc.title.alternativeActa Ophthalmolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1111/aos.16790en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed39528362en_US
bordeaux.journalActa Ophthalmologicaen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamLEHA_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDCaisse nationale de solidarité pour l'autonomieen_US
bordeaux.identifier.funderIDAgence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travailen_US
bordeaux.identifier.funderIDFondation Voir et Entendreen_US
bordeaux.import.sourcepubmed
hal.identifierhal-04806444
hal.version1
hal.date.transferred2024-11-27T09:05:45Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Acta%20Ophthalmologica&rft.date=2024-11-11&rft.eissn=1755-3768&rft.issn=1755-3768&rft.au=GAYRAUD,%20Laure&MORTAMAIS,%20Marion&SCHWEITZER,%20Cedric&DE%20HOOGH,%20Kees&GREGOIRE,%20Audrey&rft.genre=article


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