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Ambient air pollution exposure and incidence of cataract surgery: The prospective 3City-Alienor study
dc.rights.license | open | en_US |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | GAYRAUD, Laure
ORCID: 0000-0002-4381-7980 | |
dc.contributor.author | MORTAMAIS, Marion | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | SCHWEITZER, Cedric
ORCID: 0000-0002-2162-9479 IDREF: 133631583 | |
dc.contributor.author | DE HOOGH, Kees | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | GREGOIRE, Audrey
ORCID: 0000-0002-1494-5764 | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | KOROBELNIK, Jean-Francois | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | DELYFER, Marie-Noelle | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | ROUGIER, Marie-Benedicte | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | LEFFONDRE, Karen
IDREF: 183599128 | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | HELMER, Catherine | |
dc.contributor.author | VIENNEAU, Danielle | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | DELCOURT, Cecile
ORCID: 0000-0002-2099-0481 IDREF: 035105291 | |
dc.date.accessioned | 2024-11-27T09:05:38Z | |
dc.date.available | 2024-11-27T09:05:38Z | |
dc.date.issued | 2024-11-11 | |
dc.identifier.issn | 1755-3768 | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/203497 | |
dc.description.abstractEn | Cataract, the leading cause of blindness worldwide, is a multifactorial disease involving oxidative stress mechanisms. The aim of our study was to investigate the relationship between air pollution exposure and the incidence of cataract surgery. The 3C-Alienor study is a population-based cohort of residents of Bordeaux, France, aged 65 years or more, recruited in 1999-2000 and followed every 2-3 years until 2017. Cataract surgery was self-reported and checked at slit-lamp by trained professionals. Average air pollution exposure (particulate matter ≤2.5 μm (PM), black carbon (BC), nitrogen dioxide (NO)) in the 10 years preceding baseline was estimated at the participants' geocoded residential address, using temporally adjusted land use regression. Associations of 10-year average air pollution exposure with incidence of cataract were estimated using Cox proportional hazard models adjusted for confounders. The study included 829 subjects without cataract surgery prior to inclusion; the mean age at inclusion was 72.6 years (standard deviation (SD): 4.2) and 61% were women. The median (Interquartile-range (IQR)) follow-up duration was 14.1 (6.4) years during which 507 participants underwent cataract surgery. Exposure to a concentration ≥40 μg/m of NO (the current regulatory limit value in Europe) was associated with incident cataract surgery (HR = 1.46, CI (1.16, 1.84), p = 0.001). No statistically significant association was found with PM and BC. Long-term exposure to a NO concentration ≥ 40 μg/m was associated with an increased incidence of cataract surgery. Complying with current European air pollution standards could reduce cataract surgery costs and improve population quality of life. | |
dc.description.sponsorship | / | en_US |
dc.language.iso | EN | en_US |
dc.rights | Attribution 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
dc.subject.en | NO2 | |
dc.subject.en | Air Pollution | |
dc.subject.en | Cataract | |
dc.subject.en | Eye Disease | |
dc.subject.en | Fine Particulate Matter | |
dc.subject.en | Oxidative Stress | |
dc.title.en | Ambient air pollution exposure and incidence of cataract surgery: The prospective 3City-Alienor study | |
dc.title.alternative | Acta Ophthalmol | en_US |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1111/aos.16790 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
dc.identifier.pubmed | 39528362 | en_US |
bordeaux.journal | Acta Ophthalmologica | en_US |
bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | INSERM | en_US |
bordeaux.team | LEHA_BPH | en_US |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
bordeaux.identifier.funderID | Caisse nationale de solidarité pour l'autonomie | en_US |
bordeaux.identifier.funderID | Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail | en_US |
bordeaux.identifier.funderID | Fondation Voir et Entendre | en_US |
bordeaux.import.source | pubmed | |
hal.identifier | hal-04806444 | |
hal.version | 1 | |
hal.date.transferred | 2024-11-27T09:05:45Z | |
hal.popular | non | en_US |
hal.audience | Internationale | en_US |
hal.export | true | |
workflow.import.source | pubmed | |
dc.rights.cc | Pas de Licence CC | en_US |
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