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dc.rights.licenseopenen_US
dc.contributor.authorCREUZOT GARCHER, Catherine P
dc.contributor.authorMASSIN, Pascale
dc.contributor.authorSROUR, Mayer
dc.contributor.authorBAUDIN, Florian
dc.contributor.authorDOT, Corinne
dc.contributor.authorNGHIEM-BUFFET, Sylvia
dc.contributor.authorGIRMENS, Jean-Francois
dc.contributor.authorCOLLIN, Cedric
dc.contributor.authorPONTHIEUX, Anne
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDELCOURT, Cecile
ORCID: 0000-0002-2099-0481
IDREF: 035105291
dc.date.accessioned2024-11-19T13:11:13Z
dc.date.available2024-11-19T13:11:13Z
dc.date.issued2024-06-01
dc.identifier.issn1755-3768en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/203355
dc.description.abstractEnTo describe the management of diabetic macular oedema (DME) patients from the entire French population between 2012 and 2018. In this retrospective longitudinal study, we identified adults treated for DME from the French population using the exhaustive French National Health Information database (SNDS), and an algorithm based on diagnosis and procedure codes, and reimbursed treatments. Between 2012 and 2018, we identified 53 584 treated DME patients, who were followed for up to 7 years from DME treatment initiation. Optical coherence tomography (OCT) became the predominant imaging tool to diagnose DME. Only 14% of patients consulted a diabetologist or endocrinologist in the 3 months prior to initiating DME treatment, whereas 84% consulted a general practitioner. The percentage of patients consulting an ophthalmologist declined over time, from 97% of patients in Year 1 (median of 9 consultations), to 46% in Year 7 (median of 7 consultations). The median DME treatment duration with an anti-VEGF and/or dexamethasone implant treatment was 9 months; 54% of patients had a treatment duration less than 1 year. First-line treatment was more common with ranibizumab (55% of patients) than with aflibercept (30%), or dexamethasone implant (15%). About 25% of patients who initiated anti-VEGF treatment switched treatment at least once, while 30% of patients who initiated dexamethasone implant switched to anti-VEGF treatment at least once. French DME patients seem well-monitored by their ophthalmologist, but median DME treatment duration was just 9 months. These results emphasise the challenge to manage and treat patients with DME over the long term.
dc.language.isoENen_US
dc.subject.enHumans
dc.subject.enMacular Edema
dc.subject.enDiabetic Retinopathy
dc.subject.enFrance
dc.subject.enRetrospective Studies
dc.subject.enMale
dc.subject.enFemale
dc.subject.enTomography
dc.subject.enOptical Coherence
dc.subject.enIntravitreal Injections
dc.subject.enMiddle Aged
dc.subject.enAged
dc.subject.enAngiogenesis Inhibitors
dc.subject.enFollow-Up Studies
dc.subject.enGlucocorticoids
dc.subject.enVisual Acuity
dc.subject.enReceptors
dc.subject.enVascular Endothelial Growth Factor
dc.subject.enVascular Endothelial Growth Factor A
dc.subject.enDisease Management
dc.subject.enRecombinant Fusion Proteins
dc.subject.enDexamethasone
dc.subject.enRanibizumab
dc.title.enManagement of diabetic macular oedema in France from 2012 to 2018: The nationwide LANDSCAPE study
dc.title.alternativeActa Ophthalmolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1111/aos.15799en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed37874253en_US
bordeaux.journalActa Ophthalmologicaen_US
bordeaux.pagee548-e556en_US
bordeaux.volume102en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue4en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamLEHA_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-04790967
hal.version1
hal.date.transferred2024-11-19T13:11:16Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
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