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Cascade Reactions in Multicompartmentalized Polymersomes

dc.rights.licenseopen
hal.structure.identifierRadboud Univ Nijmegen, Inst Mol & Mat
dc.contributor.authorPETERS, Ruud J. R. W.
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorMARGUET, Maïté
hal.structure.identifierUniv Bordeaux Segalen, Bordeaux Imaging Ctr
dc.contributor.authorMARAIS, Sébastien
hal.structure.identifierUniv Groningen, Fac Math & Nat Sc
dc.contributor.authorFRAAIJE, Marco W.
hal.structure.identifierRadboud Univ Nijmegen, Inst Mol & Mat
dc.contributor.authorVAN HEST, Jan C. M.
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorLECOMMANDOUX, Sebastien
dc.date.accessioned2020
dc.date.available2020
dc.date.issued2014
dc.identifier.issn1433-7851
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/20330
dc.description.abstractEnEnzyme-filled polystyrene-b-poly(3-(isocyano-L-alanyl-aminoethyl)thiophene) (PS-b-PIAT) nanoreactors are encapsulated together with free enzymes and substrates in a larger polybutadiene-b-poly(ethylene oxide) (PB-b-PEO) polymersome, forming a multicompartmentalized structure, which shows structural resemblance to the cell and its organelles. An original cofactor-dependent three-enzyme cascade reaction is performed, using either compatible or incompatible enzymes, which takes place across multiple compartments.
dc.language.isoen
dc.publisherWiley-VCH Verlag
dc.subject.enpolymersomes
dc.subject.ennanoreactors
dc.subject.enartificial cells
dc.subject.encascade reactions
dc.subject.enenzyme catalysis
dc.title.enCascade Reactions in Multicompartmentalized Polymersomes
dc.typeArticle de revue
dc.identifier.doi10.1002/anie.201308141
dc.subject.halChimie/Polymères
bordeaux.journalAngewandte Chemie International Edition
bordeaux.page146-150
bordeaux.volume53
bordeaux.hal.laboratoriesLaboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629*
bordeaux.issue1
bordeaux.institutionBordeaux INP
bordeaux.institutionUniversité de Bordeaux
bordeaux.peerReviewedoui
hal.identifierhal-00959617
hal.version1
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00959617v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Angewandte%20Chemie%20International%20Edition&rft.date=2014&rft.volume=53&rft.issue=1&rft.spage=146-150&rft.epage=146-150&rft.eissn=1433-7851&rft.issn=1433-7851&rft.au=PETERS,%20Ruud%20J.%20R.%20W.&MARGUET,%20Ma%C3%AFt%C3%A9&MARAIS,%20S%C3%A9bastien&FRAAIJE,%20Marco%20W.&VAN%20HEST,%20Jan%20C.%20M.&rft.genre=article


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