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Health economic evaluation of topical treatments for external anogenital warts

dc.rights.licenseopenen_US
dc.contributor.authorAGBECI, H.
dc.contributor.authorROLLOT, O.
dc.contributor.authorDERANCOURT, C.
dc.contributor.authorBAGLIONE, Q.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBENARD, Antoine
dc.contributor.authorBERTOLOTTI, A.
dc.date.accessioned2024-10-21T09:22:51Z
dc.date.available2024-10-21T09:22:51Z
dc.date.issued2024-09-01
dc.identifier.issn0151-9638en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/202596
dc.description.abstractEnIntroduction No treatment hierarchy for external anogenital warts (AGW) is currently recommended, despite wide variations in the costs of available treatments. The aim of this study was to propose a treatment hierarchy based on a health economic analysis of local treatments for AGW from the perspective of the French health insurance system. Methods Thirteen treatments and 73 treatment sequences were evaluated for AGW clearance and absence of AGW recurrence at 3 months of follow-up. The cost per treatment included the cost of consultations, drugs, medical procedures, and dressings. The time horizon was one year. The least expensive treatment was used as the reference treatment in the calculation of incremental cost-effectiveness ratios (ICERs). A two-line decision tree for treatment was constructed. Results Podophyllotoxin 0.5% solution was the least expensive treatment. Compared to podophyllotoxin 0.5% solution, the most cost-effective treatment was surgical excision (ICER: €456.82) and the most cost-effective treatment sequence was podophyllotoxin 0.5% solution followed by 5-fluorouracil (5-FU) 5% cream. Conclusion Considering the high risk of bias in the randomized controlled trials considered, the most cost-effective treatment sequence was podophyllotoxin 0.5% solution followed by 5-FU 5% cream.
dc.language.isoENen_US
dc.subject.enAnogenital warts
dc.subject.enCost-effectiveness analysis
dc.subject.enSexually transmitted infections
dc.title.enHealth economic evaluation of topical treatments for external anogenital warts
dc.title.alternativeAnn Dermatol Venereolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.annder.2024.103288en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed39002407en_US
bordeaux.journalAnnales de Dermatologie et de Vénéréologieen_US
bordeaux.page103288en_US
bordeaux.volume151en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue3en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamPHARES_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04745979
hal.version1
hal.date.transferred2024-10-21T09:38:40Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Annales%20de%20Dermatologie%20et%20de%20V%C3%A9n%C3%A9r%C3%A9ologie&rft.date=2024-09-01&rft.volume=151&rft.issue=3&rft.spage=103288&rft.epage=103288&rft.eissn=0151-9638&rft.issn=0151-9638&rft.au=AGBECI,%20H.&ROLLOT,%20O.&DERANCOURT,%20C.&BAGLIONE,%20Q.&BENARD,%20Antoine&rft.genre=article


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