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Epidemiology of Non-Traumatic Lower Extremities Amputations in West Africa: Nationwide Data from Togo

dc.rights.licenseopenen_US
dc.contributor.authorTCHANKONI, Martin K
dc.contributor.authorTOGAN, Romeo M
dc.contributor.authorABALO, Gregoire A
dc.contributor.authorADOLI, Latame K
dc.contributor.authorWALLA, Atchi
dc.contributor.authorDOSSEH, David E
dc.contributor.authorTCHANGAI, Boyodi
dc.contributor.authorPREUX, Pierre-Marie
dc.contributor.authorABOYANS, Victor
hal.structure.identifierBordeaux population health [BPH]
hal.structure.identifierGlobal Health in the Global South [GHiGS]
dc.contributor.authorEKOUEVI, Didier Koumavi
dc.date.accessioned2024-10-14T10:22:13Z
dc.date.available2024-10-14T10:22:13Z
dc.date.issued2024-06-01
dc.identifier.issn1532-2165en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/202478
dc.description.abstractEnObjective: Non-traumatic lower limb amputation (NT-LLA) has consequences at individual and public health levels. Population based studies in sub-Saharan Africa are scarce and often related to single centre series. This study aimed to estimate the incidence of NT-LLA (minor and major) and to describe epidemiological, clinical, and prognostic aspects in Togo.Methods: This was a population based observational study conducted among all patients who underwent NT-LLA. Traumatic amputations were excluded. Sociodemographic, clinical, and work up data were collected from clinical files in any Togolese health centre from 1 January 2016 to 31 December 2021. Incidence rates were adjusted for age.Results: Over the six year period, 352 patients (59% males) underwent NT-LLA (mean ± standard deviation age 60 ± 15.7 years). The average age adjusted incidence rate of NT-LLA was 8.5 per million/year (95% confidence interval [CI] 7.6 - 9.4). Men were 1.7 times more likely to undergo a NT-LLA than women. The relative risk of NT-LLA was 48 times higher in patients with diabetes than in patients without diabetes. Around 61.0% of the NT-LLAs occurred within the 50 - 74 age group and 54.3% had diabetes mellitus. Among amputees, 54.5% had a diagnosis of peripheral artery disease (PAD) and 52.8% had diabetic ulcers, with co-existence of several factors. Less than 5% of participants had a history of smoking tobacco. Average length of hospital stay was 12 days. The in hospital mortality rate was 8.8% (9.0% for major, 6.7% for minor amputations). Only 18.2% had duplex ultrasound performed and 1.7% angiography prior to amputation. No patient underwent vascular intervention prior to amputation.Conclusion: This is the first study to report nationwide and contemporary epidemiological data on NT-LLAs in West Africa, highlighting several specificities. Large scale interventions are needed to ameliorate the care of diabetes and PAD and improve facilities for optimal management of patients at risk of amputation in Africa.
dc.language.isoENen_US
dc.subject.enDiabetes
dc.subject.enEpidemiology
dc.subject.enIncidence
dc.subject.enLimb amputation
dc.subject.enPeripheral artery disease
dc.subject.enSub-Saharan Africa
dc.title.enEpidemiology of Non-Traumatic Lower Extremities Amputations in West Africa: Nationwide Data from Togo
dc.title.alternativeEur J Vasc Endovasc Surgen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.ejvs.2024.01.088en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed38320645en_US
bordeaux.journalEuropean Journal of Vascular and Endovascular Surgeryen_US
bordeaux.page959-968en_US
bordeaux.volume67en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue6en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamGHIGS_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDInstitut de Recherche pour le Développementen_US
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=European%20Journal%20of%20Vascular%20and%20Endovascular%20Surgery&rft.date=2024-06-01&rft.volume=67&rft.issue=6&rft.spage=959-968&rft.epage=959-968&rft.eissn=1532-2165&rft.issn=1532-2165&rft.au=TCHANKONI,%20Martin%20K&TOGAN,%20Romeo%20M&ABALO,%20Gregoire%20A&ADOLI,%20Latame%20K&WALLA,%20Atchi&rft.genre=article


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