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dc.rights.licenseopenen_US
hal.structure.identifierFaculty of Physics [Vilnius]
hal.structure.identifierInterfaces, Traitements, Organisation et Dynamique des Systèmes [ITODYS (UMR_7086)]
dc.contributor.authorPARVIZIAN, M.
hal.structure.identifierFaculty of Physics [Vilnius]
hal.structure.identifierInterfaces, Traitements, Organisation et Dynamique des Systèmes [ITODYS (UMR_7086)]
dc.contributor.authorMNASRI, W.
hal.structure.identifierFaculty of Physics [Vilnius]
dc.contributor.authorPLECKAITIS, M.
hal.structure.identifierFaculty of Physics [Vilnius]
dc.contributor.authorKARABANOVAS, V.
hal.structure.identifierInterfaces, Traitements, Organisation et Dynamique des Systèmes [ITODYS (UMR_7086)]
dc.contributor.authorKHAN, H.
hal.structure.identifierInterfaces, Traitements, Organisation et Dynamique des Systèmes [ITODYS (UMR_7086)]
dc.contributor.authorNOWAK, S.
hal.structure.identifierInterfaces, Traitements, Organisation et Dynamique des Systèmes [ITODYS (UMR_7086)]
dc.contributor.authorGAM-DEROUICH, S.
hal.structure.identifierFaculté des Sciences de Bizerte [Université de Carthage]
hal.structure.identifierNorthern Border University [NBU]
dc.contributor.authorBEN TAHAR, L.
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorSANDRE, O.
hal.structure.identifierInterfaces, Traitements, Organisation et Dynamique des Systèmes [ITODYS (UMR_7086)]
dc.contributor.authorAMMAR, S.
dc.date.accessioned2024-10-05T10:16:48Z
dc.date.available2024-10-05T10:16:48Z
dc.date.issued2024-10-04
dc.identifier.issn2046-2069en_US
dc.identifier.otherhttps://recherche.data.gouv.fr/dataset.xhtml?persistentId=doi:10.82233/3RLEC2en_US
dc.identifier.urioai:crossref.org:10.1039/d4ra00909f
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/202267
dc.description.abstractEnCurrent biomedical imaging techniques are vital for the diagnosis of various diseases. They are related to the development of multimodal probes encompassing all the functionalities required for comprehensive imaging. In this context, we applied a simple and reproducible wet synthesis route to produce such probes. This method allowed us to prepare about 100 nm sized lanthanide-doped yttrium fluoride nanoparticles β-NaY0.8[Yb0.18Er0.02]F4, coated with about 10 nm sized iron oxide γ-Fe2O3 nanocrystals. By this way, the built granular hetero-nanostructures combine desirable up-converting photoluminescence (the core) and superparamagnetic properties (the satellites), enabling dual optical and magnetic resonance imaging applications. Through citrate ligand grafting, the designed core–satellite particles formed stable aqueous colloids, which are valuable for biomedical applications. Optical spectroscopy and confocal microscopy revealed their capability for sustained visible light emission (predominantly green) upon near-infrared excitation (980 nm). Additionally, based on XTT assays, when incubated for 24 hours with mammalian healthy or cancer cells, even at doses as high as 0.1 mg mL−1 (milligrams of particles), they did not induce significant cytotoxicity. The measured body temperature magnetization of the engineered nanoconstructs was found to be about 10 emu g−1 (grams of particles) at 1.5 T, which is high enough to use them as positive or negative contrast magnetic resonance agents in the clinic, as confirmed by relaxometry measurements in Milli-Q water. This result underscores their promising biomedical utility as bimodal probes for optical and magnetic imaging.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.sourcecrossref
dc.title.enUp-converting β-NaY0.8[Yb0.18Er0.02]F4 nanoparticles coated by superparamagnetic γ-Fe2O3 nanosatellites: elaboration, characterization and in vitro cytotoxicity
dc.title.alternativeRSC Adv.en_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1039/d4ra00909fen_US
dc.subject.halChimie/Matériauxen_US
bordeaux.journalRSC Advancesen_US
bordeaux.page31486-31497en_US
bordeaux.volume14en_US
bordeaux.hal.laboratoriesLaboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629en_US
bordeaux.issue43en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcedissemin
hal.identifierhal-04722512
hal.version1
hal.date.transferred2024-10-05T10:16:52Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcedissemin
dc.rights.ccCC BY-NC-SAen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=RSC%20Advances&rft.date=2024-10-04&rft.volume=14&rft.issue=43&rft.spage=31486-31497&rft.epage=31486-31497&rft.eissn=2046-2069&rft.issn=2046-2069&rft.au=PARVIZIAN,%20M.&MNASRI,%20W.&PLECKAITIS,%20M.&KARABANOVAS,%20V.&KHAN,%20H.&rft.genre=article


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