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Performance of creatinine-based equations to estimate glomerular filtration rate in White and Black populations in Europe, Brazil and Africa

dc.rights.licenseopenen_US
dc.contributor.authorDELANAYE, P.
dc.contributor.authorVIDAL-PETIOT, E.
dc.contributor.authorBJÖRK, J.
dc.contributor.authorEBERT, N.
dc.contributor.authorERIKSEN, B.O.
dc.contributor.authorDUBOURG, L.
dc.contributor.authorGRUBB, A.
dc.contributor.authorHANSSON, M.
dc.contributor.authorLITTMANN, K.
dc.contributor.authorMARIAT, C.
dc.contributor.authorMELSOM, T.
dc.contributor.authorSCHAEFFNER, E.
dc.contributor.authorSUNDIN, P.-O.
dc.contributor.authorBÖKENKAMP, A.
dc.contributor.authorBERG, U.B.
dc.contributor.authorÅSLING-MONEMI, K.
dc.contributor.authorÅKESSON, A.
dc.contributor.authorLARSSON, A.
dc.contributor.authorCAVALIER, E.
dc.contributor.authorDALTON, R.N.
dc.contributor.authorCOURBEBAISSE, M.
hal.structure.identifierImmunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle [ImmunoConcept]
dc.contributor.authorCOUZI, Lionel
dc.contributor.authorGAILLARD, F.
dc.contributor.authorGARROUSTE, C.
dc.contributor.authorJACQUEMONT, L.
dc.contributor.authorKAMAR, N.
dc.contributor.authorLEGENDRE, C.
dc.contributor.authorROSTAING, L.
dc.contributor.authorSTEHL, T.
dc.contributor.authorHAYMANN, J.-P.
dc.contributor.authorSELISTRE, L.D.S.
dc.contributor.authorSTROGOFF-DE-MATOS, J.P.
dc.contributor.authorBUKABAU, J.B.
dc.contributor.authorSUMAILI, E.K.
dc.contributor.authorYAYO, E.
dc.contributor.authorMONNET, D.
dc.contributor.authorNYMAN, U.
dc.contributor.authorPOTTEL, H.
dc.contributor.authorFLAMANT, M.
dc.date.accessioned2024-09-18T09:16:09Z
dc.date.available2024-09-18T09:16:09Z
dc.date.issued2023
dc.identifier.issn0931-0509en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/201650
dc.description.abstractEnA new Chronic Kidney Disease Epidemiology Collaboration equation without the race variable has been recently proposed (CKD-EPIAS). This equation has neither been validated outside USA nor compared with the new European Kidney Function Consortium (EKFC) and Lund-Malmö Revised (LMREV) equations, developed in European cohorts. Methods: Standardized creatinine and measured glomerular filtration rate (GFR) from the European EKFC cohorts (n = 13 856 including 6031 individuals in the external validation cohort), from France (n = 4429, including 964 Black Europeans), from Brazil (n = 100) and from Africa (n = 508) were used to test the performances of the equations. A matched analysis between White Europeans and Black Africans or Black Europeans was performed. Results: In White Europeans (n = 9496), both the EKFC and LMREV equations outperformed CKD-EPIAS (bias of -0.6 and -3.2, respectively versus 5.0 mL/min/1.73 m², and accuracy within 30% of 86.9 and 87.4, respectively, versus 80.9%). In Black Europeans and Black Africans, the best performance was observed with the EKFC equation using a specific Q-value (= concentration of serum creatinine in healthy males and females). These results were confirmed in matched analyses, which showed that serum creatinine concentrations were different in White Europeans, Black Europeans and Black Africans for the same measured GFR, age, sex and body mass index. Creatinine differences were more relevant in males. Conclusion: In a European and African cohort, the performances of CKD-EPIAS remain suboptimal. The EKFC equation, using usual or dedicated population-specific Q-values, presents the best performance in the whole age range in the European and African populations included in this study.
dc.language.isoENen_US
dc.subject.enCreatinine
dc.subject.enGlomerular filtration rate
dc.subject.enRace
dc.title.enPerformance of creatinine-based equations to estimate glomerular filtration rate in White and Black populations in Europe, Brazil and Africa
dc.typeArticle de revueen_US
dc.identifier.doi10.1093/ndt/gfac241en_US
dc.subject.halSciences du Vivant [q-bio]/Immunologieen_US
dc.identifier.pubmed36002032en_US
bordeaux.journalNephrology Dialysis Transplantationen_US
bordeaux.page106-118en_US
bordeaux.volume38en_US
bordeaux.hal.laboratoriesImmunoConcEpT - UMR 5164en_US
bordeaux.issue1en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nephrology%20Dialysis%20Transplantation&rft.date=2023&rft.volume=38&rft.issue=1&rft.spage=106-118&rft.epage=106-118&rft.eissn=0931-0509&rft.issn=0931-0509&rft.au=DELANAYE,%20P.&VIDAL-PETIOT,%20E.&BJ%C3%96RK,%20J.&EBERT,%20N.&ERIKSEN,%20B.O.&rft.genre=article


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