Tuning Thermoresponsive Properties of Cationic Elastin-like Polypeptides by Varying Counterions and Side-Chains
dc.rights.license | open | |
dc.relation.isnodouble | 470d90da-d64e-44ff-8476-dce16e47e321 | * |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
dc.contributor.author | PETITDEMANGE, Rosine | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
dc.contributor.author | GARANGER, Elisabeth
IDREF: 089451740 | |
hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
dc.contributor.author | BATAILLE, Laure | |
hal.structure.identifier | Chimie et Biologie des Membranes et des Nanoobjets [CBMN] | |
dc.contributor.author | BATHANY, Katell | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
dc.contributor.author | GARBAY, Bertrand
IDREF: 033777551 | |
hal.structure.identifier | Univ Calif Los Angeles, Dept Bioengn | |
hal.structure.identifier | Dept of Chemistry and Biochemistry, University of California, Los Angeles [UCLA] | |
dc.contributor.author | DEMING, Timothy J. | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
dc.contributor.author | LECOMMANDOUX, Sebastien | |
dc.date.accessioned | 2020 | |
dc.date.available | 2020 | |
dc.date.issued | 2017 | |
dc.identifier.issn | 1043-1802 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/20084 | |
dc.description.abstractEn | We report the synthesis of methionine-containing recombinant elastin-like polypeptides (ELPs) of different lengths that contain periodically spaced methionine residues. These ELPs were chemoselectively alkylated at all methionine residues to give polycationic derivatives. Some of these samples were found to possess solubility transitions in water, where the temperature of these transitions varied with ELP concentration, nature of the methionine alkylating group, and nature of the sulfonium counterions. These studies show that introduction and controlled spacing of methionine sulfonium residues into ELPs can be used as a means both to tune their solubility transition temperatures in water using a variety of different parameters and to introduce new side-chain functionality. | |
dc.language.iso | en | |
dc.publisher | American Chemical Society | |
dc.subject.en | Elastin-like polypeptides | |
dc.subject.en | Elastin-like peptide | |
dc.subject.en | Post-functionalization modification | |
dc.title.en | Tuning Thermoresponsive Properties of Cationic Elastin-like Polypeptides by Varying Counterions and Side-Chains | |
dc.type | Article de revue | |
dc.identifier.doi | 10.1021/acs.bioconjchem.7b00082 | |
dc.subject.hal | Chimie/Matériaux | |
dc.subject.hal | Chimie/Polymères | |
dc.subject.hal | Physique [physics]/Matière Condensée [cond-mat]/Matière Molle [cond-mat.soft] | |
dc.subject.hal | Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Biologie moléculaire | |
bordeaux.journal | Bioconjugate Chemistry | |
bordeaux.page | 1403 - 1412 | |
bordeaux.volume | 28 | |
bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
bordeaux.issue | 5 | |
bordeaux.institution | Bordeaux INP | |
bordeaux.institution | Université de Bordeaux | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-01646801 | |
hal.version | 1 | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-01646801v1 | |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Bioconjugate%20Chemistry&rft.date=2017&rft.volume=28&rft.issue=5&rft.spage=1403%20-%201412&rft.epage=1403%20-%201412&rft.eissn=1043-1802&rft.issn=1043-1802&rft.au=PETITDEMANGE,%20Rosine&GARANGER,%20Elisabeth&BATAILLE,%20Laure&BATHANY,%20Katell&GARBAY,%20Bertrand&rft.genre=article |
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