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Study protocol for two stepped-wedge interventional trials evaluating the effects of holistic information technology-based patient-oriented management in older multimorbid patients with cancer: The GERONTE trials

dc.rights.licenseopenen_US
dc.contributor.authorHAMAKER, Marije E
dc.contributor.authorWILDIERS, Hans
dc.contributor.authorARDITO, Vittoria
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorARSANDAUX, Julie
dc.contributor.authorBARTHOD-MALAT, Aurore
dc.contributor.authorDAVIES, Paul
dc.contributor.authorDEGOL, Lien
dc.contributor.authorFERRARA, Lucia
dc.contributor.authorFOURRIER, Celia
dc.contributor.authorKENIS, Cindy
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorKRET, Marion
dc.contributor.authorLALET, Caroline
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorPELISSIER, Simone Mathoulin
dc.contributor.authorO'HANLON, Shane
dc.contributor.authorROSTOFT, Siri
dc.contributor.authorSEGHERS, Nelleke
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorSAILLOUR-GLENISSON, Florence
dc.contributor.authorSTAINES, Anthony
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorSCHWIMMER, Christine
dc.contributor.authorTHEVENET, Vincent
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorWALLET, Cedric
hal.structure.identifierBoRdeaux Institute in onCology [Inserm U1312 - BRIC]
dc.contributor.authorSOUBEYRAN, Pierre
dc.date.accessioned2024-06-20T13:29:31Z
dc.date.available2024-06-20T13:29:31Z
dc.date.issued2024-05-01
dc.identifier.issn1879-4076en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/200589
dc.description.abstractEnINTRODUCTION: Current hospital-based care pathways are generally single-disease centred. As a result, coexisting morbidities are often suboptimally evaluated and managed, a deficiency becoming increasingly apparent among older patients who exhibit heterogeneity in health status, functional abilities, frailty, and other geriatric impairments. To address this issue, our study aims to assess a newly developed patient-centred care pathway for older patients with multimorbidity and cancer. The new care pathway was based on currently available evidence and co-designed by end-users including health care professionals, patients, and informal caregivers. Within this care pathway, all healthcare professionals involved in the care of older patients with multimorbidity and cancer will form a Health Professional Consortium (HPC). The role of the HPC will be to centralise oncologic and non-oncologic treatment recommendations in accordance with the patient's priorities. Moreover, an Advanced Practice Nurse will act as case-manager by being the primary point of contact for the patient, thus improving coordination between specialists, and by organising and leading the consortium. Patient monitoring and the HPC collaboration will be facilitated by digital communication tools designed specifically for this purpose, with the added benefit of being customisable for each patient. MATERIALS AND METHODS: The GERONTE study is a prospective international, multicentric study consisting of two stepped-wedge trials performed at 16 clinical sites across three European countries. Each trial will include 720 patients aged 70 years and over with a new or progressive cancer (breast, lung, colorectal, prostate) and at least one moderate or severe multimorbidity. The patients in the intervention group will receive the new care pathway whereas patients in the control group will receive usual oncologic care. DISCUSSION: GERONTE will evaluate whether this kind of holistic, patient-oriented healthcare management can improve quality of life (primary outcome) and other valuable endpoints in older patients with multimorbidity and cancer. An ancillary study will assess in depth the socio-economic impact of the intervention and deliver concrete implementation guidelines for the GERONTE intervention care pathway. TRIAL REGISTRATION: FRONE: NCT05720910 TWOBE: NCT05423808.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subject.enCancer
dc.subject.enCare pathway
dc.subject.enComprehensive geriatric assessment
dc.subject.enDigital technology
dc.subject.enGeriatric oncology
dc.subject.enTreatment decision-making
dc.title.enStudy protocol for two stepped-wedge interventional trials evaluating the effects of holistic information technology-based patient-oriented management in older multimorbid patients with cancer: The GERONTE trials
dc.title.alternativeJ Geriatr Oncolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.jgo.2024.101761en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed38581958en_US
bordeaux.journalJournal of Geriatric Oncologyen_US
bordeaux.page101761en_US
bordeaux.volume15en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue4en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamPHARES_BPHen_US
bordeaux.teamHEALTHY_BPHen_US
bordeaux.teamEPICENE_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDHorizon 2020en_US
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
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