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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorORRI, Massimiliano
dc.contributor.authorAHUN, Marilyn N
dc.contributor.authorNAICKER, Sara
dc.contributor.authorBESHARATI, Sahba
dc.contributor.authorRICHTER, Linda M
dc.date.accessioned2024-05-23T08:10:21Z
dc.date.available2024-05-23T08:10:21Z
dc.date.issued2022-03-01
dc.identifier.issn1549-1676en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/200006
dc.description.abstractEnAlthough early life factors are associated with increased suicide risk in youth, there is a dearth of research on these associations for individuals growing up in disadvantaged socioeconomic contexts, particularly in low- and middle-income countries (LMICs). We documented the association between individual, familial, and environmental factors in childhood with suicidal ideation among South African youth. We used data from 2,020 participants in the Birth to Twenty Plus (Bt20+) study, a South African cohort following children born in Soweto, Johannesburg from birth (1990) to age 28 years (2018). Suicidal ideation was self-reported at ages 14, 17, 22, and 28 years, and the primary outcome of interest was suicidal ideation reported at any age. We assessed individual, familial, and socioeconomic characteristics at childbirth and during infancy, adverse childhood experiences (ACEs) between ages 5 and 13 years, and externalizing and internalizing problems between 5 and 10 years. We estimated odds ratios (ORs) of suicidal ideation for individuals exposed to selected childhood factors using logistic regression. Lifetime suicidal ideation was reported by 469 (23.2%) participants, with a 1.7:1 female/male ratio. Suicidal ideation rates peaked at age 17 and decreased thereafter. Socioeconomic adversity, low birth weight, higher birth order (i.e., increase in the order of birth in the family: first, second, third, fourth, or later born child), ACEs, and childhood externalizing problems were associated with suicidal ideation, differently patterned among males and females. Socioeconomic adversity (OR 1.13, CI 1.01 to 1.27, P = 0.031) was significantly associated with suicidal ideation among males only, while birth weight (OR 1.20, CI 1.02 to 1.41, P = 0.03), ACEs (OR 1.11, CI 1.01 to 1.21, P = 0.030), and higher birth order (OR 1.15, CI 1.07 to 1.243, P < 0.001) were significantly associated with suicidal ideation among females only. Externalizing problems in childhood were significantly associated with suicidal ideation among both males (OR 1.23, 1.08 to 1.40, P = 0.002) and females (OR 1.16, CI 1.03 to 1.30, P = 0.011). Main limitations of the study are the high attrition rate (62% of the original sample was included in this analysis) and the heterogeneity in the measurements of suicidal ideation. In this study from South Africa, we observed that early life social and environmental adversities as well as childhood externalizing problems are associated with increased risk of suicidal ideation during adolescence and early adulthood.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enAdolescent
dc.subject.enAdult
dc.subject.enChild
dc.subject.enChild
dc.subject.enPreschool
dc.subject.enCohort Studies
dc.subject.enFemale
dc.subject.enHumans
dc.subject.enLongitudinal Studies
dc.subject.enMale
dc.subject.enRisk Factors
dc.subject.enSouth Africa
dc.subject.enSuicidal Ideation
dc.subject.enSuicide
dc.title.enChildhood factors associated with suicidal ideation among South African youth: A 28-year longitudinal study of the Birth to Twenty Plus cohort.
dc.title.alternativePLoS Meden_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1371/journal.pmed.1003946en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed35290371en_US
bordeaux.journalPLoS Medicineen_US
bordeaux.pagee1003946en_US
bordeaux.volume19en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue3en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamHEALTHY_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDHorizon 2020en_US
bordeaux.identifier.funderIDBill and Melinda Gates Foundationen_US
bordeaux.import.sourcepubmed
hal.identifierhal-04584382
hal.version1
hal.date.transferred2024-05-23T08:10:23Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.jtitle=PLoS%20Medicine&amp;rft.date=2022-03-01&amp;rft.volume=19&amp;rft.issue=3&amp;rft.spage=e1003946&amp;rft.epage=e1003946&amp;rft.eissn=1549-1676&amp;rft.issn=1549-1676&amp;rft.au=ORRI,%20Massimiliano&amp;AHUN,%20Marilyn%20N&amp;NAICKER,%20Sara&amp;BESHARATI,%20Sahba&amp;RICHTER,%20Linda%20M&amp;rft.genre=article


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