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dc.rights.licenseopenen_US
dc.contributor.authorDUPRAZ, Valentin
hal.structure.identifierLaboratoire Universitaire de Biodiversité et Ecologie Microbienne [LUBEM]
dc.contributor.authorSTACHOWSKI-HABERKORN, Sabine
hal.structure.identifierCentre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
dc.contributor.authorMENARD, Dominique
hal.structure.identifierLABOCEA Laboratoire [Plouzané, France]
dc.contributor.authorLIMON, Gwendolina
hal.structure.identifierUnité Biogéochimie et Ecotoxicologie [BE]
dc.contributor.authorAKCHA, Farida
hal.structure.identifierLaboratoire de Physico et Toxico-Chimie des systèmes naturels [LPTC]
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorBUDZINSKI, Hélène
ORCID: 0000-0003-1028-9154
IDREF: 070478090
dc.contributor.authorCEDERGREEN, Nina
dc.date.accessioned2024-05-22T16:39:32Z
dc.date.available2024-05-22T16:39:32Z
dc.date.issued2018-10
dc.identifier.issn0045-6535en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/200001
dc.description.abstractEnThe toxicity of the antifouling compounds diuron, irgarol, zinc pyrithione (ZnPT), copper pyrithione (CuPT) and copper was tested on the three marine microalgae Tisochrysis lutea, Skeletonema marinoi and Tetraselmis suecica. Toxicity tests based on the inhibition of growth rate after 96-h exposure were run using microplates. Chemical analyses were performed to validate the exposure concentrations and the stability of the compounds under test conditions. Single chemicals exhibited varying toxicity depending on the species, irgarol being the most toxic chemical and Cu the least toxic. Selected binary mixtures were tested and the resulting interactions were analyzed using two distinct concentration-response surface models: one using the concentration addition (CA) model as reference and two deviating isobole models implemented in R software; the other implementing concentration-response surface models in Excel®, using both CA and independent action (IA) models as reference and three deviating models. Most mixtures of chemicals sharing the same mode of action (MoA) were correctly predicted by the CA model. For mixtures of dissimilarly acting chemicals, neither of the reference models provided better predictions than the other. Mixture of ZnPT together with Cu induced a strong synergistic effect on T. suecica while strong antagonism was observed on the two other species. The synergy was due to the transchelation of ZnPT into CuPT in the presence of Cu, CuPT being 14-fold more toxic than ZnPT for this species. The two modelling approaches are compared and the differences observed among the interaction patterns resulting from the mixtures are discussed.
dc.language.isoENen_US
dc.title.enCombined effects of antifouling biocides on the growth of three marine microalgal species
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.chemosphere.2018.06.139en_US
dc.subject.halSciences de l'environnementen_US
bordeaux.journalChemosphereen_US
bordeaux.page801-814en_US
bordeaux.volume209en_US
bordeaux.hal.laboratoriesEPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.teamLPTCen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-02336924
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Chemosphere&rft.date=2018-10&rft.volume=209&rft.spage=801-814&rft.epage=801-814&rft.eissn=0045-6535&rft.issn=0045-6535&rft.au=DUPRAZ,%20Valentin&STACHOWSKI-HABERKORN,%20Sabine&MENARD,%20Dominique&LIMON,%20Gwendolina&AKCHA,%20Farida&rft.genre=article


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