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dc.rights.licenseopenen_US
hal.structure.identifierAcceptables Avenirs
dc.contributor.authorDESTRIEUX, Doriane
hal.structure.identifierMétabolisme et Xénobiotiques [ToxAlim-MeX]
dc.contributor.authorLAURENT, Francois
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorBUDZINSKI, Hélène
ORCID: 0000-0003-1028-9154
IDREF: 070478090
hal.structure.identifierCentre National de la Recherche Scientifique [CNRS]
dc.contributor.authorPÉDELUCQ, Julie
hal.structure.identifierAcceptables Avenirs
dc.contributor.authorVERVIER, Philippe
hal.structure.identifierLaboratoire Ecologie Fonctionnelle et Environnement [LEFE]
dc.contributor.authorGÉRINO, Magali
dc.date.accessioned2024-05-13T16:13:47Z
dc.date.available2024-05-13T16:13:47Z
dc.date.issued2017
dc.identifier.issn0048-9697en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/199802
dc.description.abstractEnHuman-use drug residues (DR) are only partially eliminated by waste water treatment plants (WWTPs), so that residual amounts can reach natural waters and cause environmental hazards. In order to properly manage these hazards in the aquatic environment, a database is made available that integrates the concentration ranges for DR, which cause adverse effects for aquatic organisms, and the temporal variations of the ecotoxicological risks. To implement this database for the ecotoxicological risk assessment (ERA database), the required information for each DR is the predicted no effect concentrations (PNECs), along with the predicted environmental concentrations (PECs). The risk assessment is based on the ratio between the PNECs and the PECs. Adverse effect data or PNECs have been found in the publicly available literature for 45 substances. These ecotoxicity test data have been extracted from 125 different sources. This ERA database contains 1157 adverse effect data and 287 PNECs. The efficiency of this ERA database was tested with a data set coming from a simultaneous survey of WWTPs and the natural environment. In this data set, 26 DR were searched for in two WWTPs and in the river. On five sampling dates, concentrations measured in the river for 10 DR could pose environmental problems of which 7 were measured only downstream of WWTP outlets. From scientific literature and measurements, data implementation with unit homogenisation in a single database facilitates the actual ecotoxicological risk assessment, and may be useful for further risk coming from data arising from the future field survey. Moreover, the accumulation of a large ecotoxicity data set in a single database should not only improve knowledge of higher risk molecules but also supply an objective tool to help the rapid and efficient evaluation of the risk.
dc.language.isoENen_US
dc.subjectpharmaceuticals
dc.subject.enecotoxicological risk
dc.subject.enpredicted no effect concentration
dc.subject.enadverse effects
dc.subject.enpredicted environmental concentration
dc.subject.endatabase
dc.title.enDrug residues in urban water: A database for ecotoxicological risk management
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.scitotenv.2017.07.043en_US
dc.subject.halSciences de l'environnement/Environnement et Sociétéen_US
bordeaux.journalScience of the Total Environmenten_US
bordeaux.page927-941en_US
bordeaux.volume609en_US
bordeaux.hal.laboratoriesEPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.teamLPTCen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-02625291
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Science%20of%20the%20Total%20Environment&rft.date=2017&rft.volume=609&rft.spage=927-941&rft.epage=927-941&rft.eissn=0048-9697&rft.issn=0048-9697&rft.au=DESTRIEUX,%20Doriane&LAURENT,%20Francois&BUDZINSKI,%20H%C3%A9l%C3%A8ne&P%C3%89DELUCQ,%20Julie&VERVIER,%20Philippe&rft.genre=article


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