Afficher la notice abrégée

Transcriptomic, Biochemical, and Histopathological Responses of the Clam Ruditapes decussatus from a Metal-Contaminated Tunis Lagoon

dc.rights.licenseopenen_US
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorCHALGHMI, Houssem
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorBOURDINEAUD, Jean-Paul
dc.contributor.authorHAOUAS, Zohra
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorGOURVES, Pierre Yves
dc.contributor.authorZRAFI, Ines
dc.contributor.authorSAIDANE-MOSBAHI, Dalila
dc.date.accessioned2024-05-13T09:42:51Z
dc.date.available2024-05-13T09:42:51Z
dc.date.issued2015-06-16
dc.identifier.issn0090-4341en_US
dc.identifier.urihttps://www.researchgate.net/publication/278732289_Transcriptomic_Biochemical_and_Histopathological_Responses_of_the_Clam_Ruditapes_decussatus_from_a_Metal-Contaminated_Tunis_Lagoon
dc.identifier.urioai:crossref.org:10.1007/s00244-015-0185-0
dc.identifier.urioai:researchgate.net:278732289
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/199780
dc.description.abstractEnThis study was designed to investigate the molecular (transcriptional expression), biochemical (oxidative stress and neurotoxicity), and histopathological effects of metal contamination in the gill of clams (Ruditapes decussatus) sampled from the Tunis lagoon. The concentrations of five heavy metals (Cd, Pb, Hg, Cu, and Zn) in surface sediments and their accumulation in soft tissues of R. decussatus were evaluated in three sites (Z1, Z2, and Z3). A metal contamination state of Tunis lagoon sediments was noted with spatial variations with relatively high levels at Z2. Biomarker analyses showed an increase in glutathione S-transferase and catalase activities and lipid peroxidation levels and a decrease in acetylcholinesterase activity in the studied sites. Molecular investigation showed a significant overexpression of: cytochrome c oxidase subunit I, ribosomal RNA 16S, Cu/Zn superoxide dismutase, heat shock protein 70, and metallothioneins in the three sampling sites. Moreover, our data were correlated to severe and diverse histopathological alterations in the clam gills. The principal component analysis showed that the Z2 region is more affected by metal contamination than Z1 and Z3 regions. Current field results suggest the use of several combined biomarkers at different cell levels instead of individual ones in monitoring programs.
dc.language.isoENen_US
dc.sourcecrossref
dc.sourceresearchgate
dc.title.enTranscriptomic, Biochemical, and Histopathological Responses of the Clam Ruditapes decussatus from a Metal-Contaminated Tunis Lagoon
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s00244-015-0185-0en_US
dc.subject.halSciences de l'environnementen_US
bordeaux.journalArchives of Environmental Contamination and Toxicologyen_US
bordeaux.page241-256en_US
bordeaux.volume70en_US
bordeaux.hal.laboratoriesEPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805en_US
bordeaux.issue2en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.teamEAen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcedissemin
hal.identifierhal-04573319
hal.version1
hal.date.transferred2024-05-13T09:42:52Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcedissemin
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Archives%20of%20Environmental%20Contamination%20and%20Toxicology&rft.date=2015-06-16&rft.volume=70&rft.issue=2&rft.spage=241-256&rft.epage=241-256&rft.eissn=0090-4341&rft.issn=0090-4341&rft.au=CHALGHMI,%20Houssem&BOURDINEAUD,%20Jean-Paul&HAOUAS,%20Zohra&GOURVES,%20Pierre%20Yves&ZRAFI,%20Ines&rft.genre=article


Fichier(s) constituant ce document

FichiersTailleFormatVue

Il n'y a pas de fichiers associés à ce document.

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée