Polymersome Popping by Light-Induced Osmotic Shock under Temporal, Spatial, and Spectral Control
dc.rights.license | open | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
dc.contributor.author | PEYRET, Ariane | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
dc.contributor.author | IBARBOURE, Emmanuel | |
hal.structure.identifier | Institut des Sciences Moléculaires [ISM] | |
dc.contributor.author | TRON, Arnaud | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
dc.contributor.author | BEAUTÉ, Louis | |
hal.structure.identifier | Institut des Sciences Moléculaires [ISM] | |
dc.contributor.author | RUST, Ruben | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
dc.contributor.author | SANDRE, Olivier | |
hal.structure.identifier | Institut des Sciences Moléculaires [ISM] | |
dc.contributor.author | MCCLENAGHAN, Nathan | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
dc.contributor.author | LECOMMANDOUX, Sebastien | |
dc.date.accessioned | 2020 | |
dc.date.available | 2020 | |
dc.date.issued | 2017 | |
dc.identifier.issn | 1433-7851 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/19975 | |
dc.description.abstractEn | The light-triggered, programmable rupture of cellsized vesicles is described, with particular emphasis on selfassembled polymersome capsules. The mechanism involves a hypotonic osmotic imbalance created by the accumulation of photogenerated species inside the lumen, which cannot be compensated owing to the low water permeability of the membrane. This simple and versatile mechanism can be adapted to a wealth of hydrosoluble molecules, which are either able to generate reactive oxygen species or undergo photocleavage. Ultimately, in a multi-compartmentalized and cell-like system, the possibility to selectively burst polymersomes with high specificity and temporal precision and to consequently deliver small encapsulated vesicles (both polymersomes and liposomes) is demonstrated. | |
dc.description.sponsorship | Développement de cellule synthétique comme micro-réacteur pour l'étude de l'activité enzymatique des NO-synthases et la compréhension de leur fonctionnement en conditions physiologiques - ANR-14-CE16-0015 | |
dc.language.iso | en | |
dc.publisher | Wiley-VCH Verlag | |
dc.subject.en | Membrane proes | |
dc.subject.en | Polymerosomes | |
dc.subject.en | Liposomes | |
dc.subject.en | Osmotic pressure | |
dc.subject.en | Photochemistry | |
dc.subject.en | Coumarin | |
dc.subject.en | Uncaging | |
dc.title.en | Polymersome Popping by Light-Induced Osmotic Shock under Temporal, Spatial, and Spectral Control | |
dc.type | Article de revue | |
dc.identifier.doi | 10.1002/ange.201609231 | |
dc.subject.hal | Chimie/Matériaux | |
dc.subject.hal | Chimie/Polymères | |
bordeaux.journal | Angewandte Chemie International Edition | |
bordeaux.page | 1566-1570 | |
bordeaux.volume | 56 | |
bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
bordeaux.issue | 6 | |
bordeaux.institution | Bordeaux INP | |
bordeaux.institution | Université de Bordeaux | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-01418924 | |
hal.version | 1 | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-01418924v1 | |
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