Toxicity assessment of water-accommodated fractions from two different oils using a zebrafish (Danio rerio) embryo-larval bioassay with a multilevel approach
| dc.rights.license | open | en_US |
| hal.structure.identifier | LIttoral ENvironnement et Sociétés [LIENSs] | |
| hal.structure.identifier | Unité Biogéochimie et Ecotoxicologie [BE] | |
| dc.contributor.author | PERRICHON, Prescilla | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | LE MENACH, Karyn
IDREF: 256879966 | |
| hal.structure.identifier | Unité Biogéochimie et Ecotoxicologie [BE] | |
| dc.contributor.author | AKCHA, Farida | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | CACHOT, Jérôme
ORCID: 0000-0002-1492-9684 IDREF: 19667672X | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | BUDZINSKI, Hélène
ORCID: 0000-0003-1028-9154 IDREF: 070478090 | |
| hal.structure.identifier | LIttoral ENvironnement et Sociétés [LIENSs] | |
| dc.contributor.author | BUSTAMANTE, Paco | |
| dc.date.accessioned | 2024-04-17T11:57:22Z | |
| dc.date.available | 2024-04-17T11:57:22Z | |
| dc.date.issued | 2016-10-15 | |
| dc.identifier.issn | 0048-9697 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/199199 | |
| dc.description.abstractEn | Petroleum compounds from chronic discharges and oil spills represent an important source of environmental pollution. To better understand the deleterious effects of these compounds, the toxicity of water-accommodated fractions (WAF) from two different oils (brut Arabian Light and Erika heavy fuel oils) were used in this study. Zebrafish embryos (Danio rerio) were exposed during 96 hours at three WAF concentrations (1, 10 and 100% for Arabian Light and 10, 50 and 100% for Erika) in order to cover a wide range of polycyclic aromatic hydrocarbon (PAH) concentrations, representative of the levels found after environmental oil spills. Several endpoints were recorded at different levels of biological organization, including lethal endpoints, morphological abnormalities, photomotor behavioral responses, cardiac activity, DNA damage and exposure level measurements (EROD activity, cyp1a and PAH metabolites). Neither morphological nor behavioral or physiological alterations were observed after exposure to Arabian Light fractions. In contrast, the Erika fractions led a high degree of toxicity in early life stages of zebrafish. Despite of defense mechanisms induced by oil, acute toxic effects have been recorded including mortality, delayed hatching, high rates of developmental abnormalities, disrupted locomotor activity and cardiac failures at the highest PAH concentrations (Σ TPAHs=257029 ± 47231 ng.L-1). Such differences in toxicity are likely related to the oil composition. The use of developing zebrafish is a good tool to identify wide range of detrimental effects and elucidate their underlying foundations. Our work highlights once more, the cardiotoxic action (and potentially neurotoxic) of petroleum-related PAHs. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Zebrafish embryos | |
| dc.subject.en | oil exposure | |
| dc.subject.en | teratogenicity | |
| dc.subject.en | swimming performance | |
| dc.subject.en | bradycardia | |
| dc.subject.en | detoxification pathway | |
| dc.subject.en | Zebrafish embryos | |
| dc.title.en | Toxicity assessment of water-accommodated fractions from two different oils using a zebrafish (Danio rerio) embryo-larval bioassay with a multilevel approach | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.scitotenv.2016.04.186 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Toxicologie/Ecotoxicologie | en_US |
| bordeaux.journal | Science of the Total Environment | en_US |
| bordeaux.page | 952–966 | en_US |
| bordeaux.volume | 568 | en_US |
| bordeaux.hal.laboratories | EPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | hal | |
| hal.identifier | hal-01385694 | |
| hal.version | 1 | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | false | |
| workflow.import.source | hal | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Science%20of%20the%20Total%20Environment&rft.date=2016-10-15&rft.volume=568&rft.spage=952%E2%80%93966&rft.epage=952%E2%80%93966&rft.eissn=0048-9697&rft.issn=0048-9697&rft.au=PERRICHON,%20Prescilla&LE%20MENACH,%20Karyn&AKCHA,%20Farida&CACHOT,%20J%C3%A9r%C3%B4me&BUDZINSKI,%20H%C3%A9l%C3%A8ne&rft.genre=article |
