Investigating the response of cuproproteins from oysters (Crassostrea gigas) after waterborne copper exposure by metallomic and proteomic approaches
| dc.rights.license | open | en_US |
| dc.contributor.author | XU, Ming | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | BIJOUX, Hugues | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | GONZALEZ, Patrice
ORCID: 0000-0003-2628-2993 IDREF: 14341917X | |
| dc.contributor.author | MOUNICOU, Sandra | |
| dc.date.accessioned | 2024-04-16T09:45:09Z | |
| dc.date.available | 2024-04-16T09:45:09Z | |
| dc.date.issued | 2014-01-15 | |
| dc.identifier.issn | 1756-5901 | en_US |
| dc.identifier.uri | https://www.researchgate.net/publication/259767089_Investigating_the_response_of_cuproproteins_from_oysters_Crassostrea_gigas_after_waterborne_copper_exposure_by_metallomic_and_proteomic_approaches | |
| dc.identifier.uri | oai:crossref.org:10.1039/c3mt00375b | |
| dc.identifier.uri | oai:researchgate.net:259767089 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/199089 | |
| dc.description.abstractEn | The pacific oyster (Crassostrea gigas), a good model for studying biomineralization and coastal environmental change, was used to study the expression of cuproproteins after waterborne Cu exposure (3 μg Cu L(-1)) similarly to the Arcachon Bay aquatic environment. Cuproproteins in oyster cytosols were analyzed by gel electrophoresis (non-denaturing PAGE and SDS 2-DE), laser ablation inductively coupled plasma mass spectrometry (LA-ICP MS) and electrospray ionization mass spectrometry (ESI-MS). The high molecular weight cuproproteins (identified as extracellular superoxide dismutase [Cu-Zn] (EC Cu/Zn-SOD) and l-ascorbate oxidase) in digestive glands of oysters were differentially expressed after Cu exposure. About 1.7 and 1.2-fold increase of the Cu level in EC Cu/Zn-SOD and l-ascorbate oxidase were, respectively, determined, although EC Cu/Zn-SOD was 1.6-1.9-fold down-regulated in the digestive gland of oysters after Cu exposure. At last, the role of EC Cu/Zn-SOD in protection against Cu exposure was discussed to propose possible mechanisms to better understand Cu homeostasis and/or detoxification mechanisms. | |
| dc.language.iso | EN | en_US |
| dc.source | crossref | |
| dc.source | researchgate | |
| dc.title.en | Investigating the response of cuproproteins from oysters (Crassostrea gigas) after waterborne copper exposure by metallomic and proteomic approaches | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1039/c3mt00375b | en_US |
| dc.subject.hal | Sciences de l'environnement | en_US |
| bordeaux.journal | Metallomics | en_US |
| bordeaux.page | 338 | en_US |
| bordeaux.volume | 6 | en_US |
| bordeaux.hal.laboratories | EPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805 | en_US |
| bordeaux.issue | 2 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.team | EA | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | dissemin | |
| hal.identifier | hal-04548196 | |
| hal.version | 1 | |
| hal.date.transferred | 2024-04-16T09:45:11Z | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | true | |
| workflow.import.source | dissemin | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Metallomics&rft.date=2014-01-15&rft.volume=6&rft.issue=2&rft.spage=338&rft.epage=338&rft.eissn=1756-5901&rft.issn=1756-5901&rft.au=XU,%20Ming&BIJOUX,%20Hugues&GONZALEZ,%20Patrice&MOUNICOU,%20Sandra&rft.genre=article |
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