Mostrar el registro sencillo del ítem
Transcriptomic responses of the endangered freshwater mussel Margaritifera margaritifera to trace metal contamination in the Dronne River, France
| dc.rights.license | open | en_US |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | BERTUCCI, Anthony | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | PIERRON, Fabien | |
| hal.structure.identifier | Laboratoire des Sciences de l'Environnement Marin (LEMAR) [LEMAR] | |
| dc.contributor.author | THÉBAULT, Julien | |
| hal.structure.identifier | Génome et Transcriptome - Plateforme Génomique [ GeT-PlaGe] | |
| hal.structure.identifier | Unité de Mathématiques et Informatique Appliquées de Toulouse [MIAT INRAE] | |
| dc.contributor.author | KLOPP, Christophe | |
| hal.structure.identifier | Laboratoire des Sciences de l'Environnement Marin (LEMAR) [LEMAR] | |
| dc.contributor.author | BELLEC, Julie | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | GONZALEZ, Patrice
ORCID: 0000-0003-2628-2993 IDREF: 14341917X | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | BAUDRIMONT, Magalie
IDREF: 105696722 | |
| dc.date.accessioned | 2024-04-10T12:05:59Z | |
| dc.date.available | 2024-04-10T12:05:59Z | |
| dc.date.issued | 2017 | |
| dc.identifier.issn | 0944-1344 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/197414 | |
| dc.description.abstractEn | The freshwater pearl mussel Margaritifera margaritifera is one of the most threatened freshwater bivalves worldwide. In this study, we aimed (i) to study the processes by which water quality might affect freshwater mussels in situ and (ii) to provide insights into the ecotoxicological significance of water pollution to natural populations in order to provide necessary information to enhance conservation strategies. M. margaritifera specimens were sampled in two close sites located upstream or downstream from an illegal dumping site. The renal transcriptome of these animals was assembled and gene transcription determined by RNA-seq. Correlations between transcription levels of each single transcript and the bioaccumulation of nine trace metals, age (estimated by sclerochronology), and condition index were determined in order to identify genes likely to respond to a specific factor. Amongst the studied metals, Cr, Zn, Cd, and Ni were the main factors correlated with transcription levels, with effects on translation, apoptosis, immune response, response to stimulus, and transport pathways. However, the main factor explaining changes in gene transcription appeared to be the age of individuals with a negative correlation with the transcription of retrotransposon-related genes. To investigate this effect further, mussels were classified into three age classes. In young, middle-aged and old animals, transcription levels were mainly explained by Cu, Zn and age, respectively. This suggests differences in the molecular responses of this species to metals during its lifetime that must be better assessed in future ecotoxicology studies. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | ACL | |
| dc.subject.en | Freshwater mussel | |
| dc.subject.en | Transcriptomics | |
| dc.subject.en | RNA sequencing | |
| dc.subject.en | Metal pollution | |
| dc.subject.en | Sclerochronology | |
| dc.subject.en | Margaritifera margaritifera | |
| dc.subject.en | In situ study | |
| dc.title.en | Transcriptomic responses of the endangered freshwater mussel Margaritifera margaritifera to trace metal contamination in the Dronne River, France | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1007/s11356-017-0294-6 | en_US |
| dc.subject.hal | Sciences de l'environnement/Biodiversité et Ecologie | en_US |
| bordeaux.journal | Environmental Science and Pollution Research | en_US |
| bordeaux.page | 27145-27159 | en_US |
| bordeaux.volume | 24 | en_US |
| bordeaux.hal.laboratories | EPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805 | en_US |
| bordeaux.issue | 35 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.team | EA | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | hal | |
| hal.identifier | hal-02571118 | |
| hal.version | 1 | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | false | |
| workflow.import.source | hal | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Environmental%20Science%20and%20Pollution%20Research&rft.date=2017&rft.volume=24&rft.issue=35&rft.spage=27145-27159&rft.epage=27145-27159&rft.eissn=0944-1344&rft.issn=0944-1344&rft.au=BERTUCCI,%20Anthony&PIERRON,%20Fabien&TH%C3%89BAULT,%20Julien&KLOPP,%20Christophe&BELLEC,%20Julie&rft.genre=article |
Archivos en el ítem
| Archivos | Tamaño | Formato | Ver |
|---|---|---|---|
|
No hay archivos asociados a este ítem. |
|||