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A Computational Investigation into the Effect of Infarction on Clinical Human Electrophysiology Biomarkers
hal.structure.identifier | Computing Science Laboratory - Oxford University | |
dc.contributor.author | CARDONE-NOOTT, Louie | |
hal.structure.identifier | Computing Science Laboratory - Oxford University | |
dc.contributor.author | BUENO-OROVIO, Alfonso | |
hal.structure.identifier | Computing Science Laboratory - Oxford University | |
dc.contributor.author | MINCHOLÉ, Ana | |
hal.structure.identifier | The University of Queensland [UQ [All campuses : Brisbane, Dutton Park Gatton, Herston, St Lucia and other locations]] | |
hal.structure.identifier | Computing Science Laboratory - Oxford University | |
dc.contributor.author | BURRAGE, Kevin | |
hal.structure.identifier | Fraunhofer-Chalmers Center [Gothenburg] [FCC] | |
hal.structure.identifier | Computing Science Laboratory - Oxford University | |
dc.contributor.author | WALLMAN, Mikael | |
hal.structure.identifier | Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN] | |
dc.contributor.author | ZEMZEMI, Nejib | |
hal.structure.identifier | Radcliffe Department of Medicine [Oxford] | |
hal.structure.identifier | Computing Science Laboratory - Oxford University | |
dc.contributor.author | DALL'ARMELLINA, Erica | |
hal.structure.identifier | Computing Science Laboratory - Oxford University | |
dc.contributor.author | BLANCA, Rodriguez | |
dc.date.accessioned | 2024-04-04T03:20:31Z | |
dc.date.available | 2024-04-04T03:20:31Z | |
dc.date.issued | 2014-09-08 | |
dc.date.conference | 2014-09-08 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/194593 | |
dc.description.abstractEn | The electrocardiogram (ECG) is often used to diag- nose myocardial infarction, but sensitivity and specificity are low. Here we present a computational framework for solving the bidomain equations over an image-based hu- man geometry and simulating the 12 lead ECG. First, we demonstrate this approach by evaluating a population of eight models with varying distributions of local action po- tential duration, and report that only the model with apico- basal and inter-ventricular heterogeneities produces concordant T waves. Second, we simulate the effects of an old anterior infarct, which causes a reduction in T wave amplitude and width. Our methodology can contribute to the understanding of ECG alterations under challenging conditions for clinical diagnosis. | |
dc.language.iso | en | |
dc.title.en | A Computational Investigation into the Effect of Infarction on Clinical Human Electrophysiology Biomarkers | |
dc.type | Communication dans un congrès | |
dc.subject.hal | Informatique [cs] | |
bordeaux.hal.laboratories | Institut de Mathématiques de Bordeaux (IMB) - UMR 5251 | * |
bordeaux.institution | Université de Bordeaux | |
bordeaux.institution | Bordeaux INP | |
bordeaux.institution | CNRS | |
bordeaux.conference.title | IEEE Computers in Cardiology | |
bordeaux.country | US | |
bordeaux.conference.city | Cambridge | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-01065716 | |
hal.version | 1 | |
hal.invited | non | |
hal.proceedings | oui | |
hal.conference.end | 2014-09-10 | |
hal.popular | non | |
hal.audience | Internationale | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-01065716v1 | |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.date=2014-09-08&rft.au=CARDONE-NOOTT,%20Louie&BUENO-OROVIO,%20Alfonso&MINCHOL%C3%89,%20Ana&BURRAGE,%20Kevin&WALLMAN,%20Mikael&rft.genre=unknown |
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