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Measurement of Glomerular Filtration Rate With Magnetic Resonance Imaging: Principles, Limitations, and Expectations

hal.structure.identifierImagerie moléculaire et fonctionnelle: de la physiologie à la thérapie
dc.contributor.authorGRENIER, Nicolas
hal.structure.identifierRadiology & Physics Unit, UCL Institute of Child Health
dc.contributor.authorMENDICHOVSZKY, Iosif
hal.structure.identifierInstitut de Mathématiques de Bordeaux [IMB]
dc.contributor.authorDENIS DE SENNEVILLE, Baudouin
hal.structure.identifierImagerie moléculaire et fonctionnelle: de la physiologie à la thérapie
dc.contributor.authorROUJOL, Sébastien
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
dc.contributor.authorDESBARAT, Pascal
hal.structure.identifierInstitute of Clinical Medicine [Oslo]
dc.contributor.authorPEDERSEN, Michael
hal.structure.identifierSchool of Electronics and Physical Sciences
dc.contributor.authorWELLS, Kevin
hal.structure.identifierInstitute of Clinical Medicine [Oslo]
dc.contributor.authorFROKIAER, Jorgen
hal.structure.identifierRadiology & Physics Unit, UCL Institute of Child Health
dc.contributor.authorGORDON, Isky
dc.date.accessioned2024-04-04T03:10:31Z
dc.date.available2024-04-04T03:10:31Z
dc.date.issued2008
dc.identifier.issn0001-2998
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/193691
dc.description.abstractEnGlomerular filtration rate (GFR) is the most useful quantitative index of renal function and is used clinically as the gold standard of renal dysfunction. Follow-up of patients with impaired renal function requires reliable measurements of GFR. Thus, serial GFR values estimated from magnetic resonance imaging (MRI) would be worthwhile if easy to obtain, accurate, and reproducible. Nuclear medicine-based techniques remain at present the reference method for quantification of GFR, but MRI should be able to compete in the near future. Several methods are available for measurement of GFR using MRI and freely filtered Gd-chelates: (1) measurement of the clearance of the agent using blood samplings; (2) measurement of the clearance of the agent using signal intensity changes within abdominal organs; (3) measurement of the extraction fraction of the agent; and (4) monitoring of tracer intrarenal kinetics. A high heter-ogeneity of protocols (e.g., in acquisition mode, dose of contrast, postprocessing techniques) is noted in the literature, reflecting the number of technical challenges that will have to be solved before to reach a consensus, and the reported accuracy and reproducibility are insufficient for justifying their use in clinical practice now.
dc.language.isoen
dc.publisherElsevier
dc.title.enMeasurement of Glomerular Filtration Rate With Magnetic Resonance Imaging: Principles, Limitations, and Expectations
dc.typeArticle de revue
dc.identifier.doi10.1053/j.semnuclmed.2007.09.004
dc.subject.halSciences de l'ingénieur [physics]/Traitement du signal et de l'image
dc.subject.halSciences du Vivant [q-bio]/Ingénierie biomédicale/Imagerie
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologie/Urologie et Néphrologie
bordeaux.journalSeminars in Nuclear Medicine
bordeaux.page47-55
bordeaux.volume38
bordeaux.hal.laboratoriesInstitut de Mathématiques de Bordeaux (IMB) - UMR 5251*
bordeaux.issue1
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierhal-01503900
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-01503900v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Seminars%20in%20Nuclear%20Medicine&rft.date=2008&rft.volume=38&rft.issue=1&rft.spage=47-55&rft.epage=47-55&rft.eissn=0001-2998&rft.issn=0001-2998&rft.au=GRENIER,%20Nicolas&MENDICHOVSZKY,%20Iosif&DENIS%20DE%20SENNEVILLE,%20Baudouin&ROUJOL,%20S%C3%A9bastien&DESBARAT,%20Pascal&rft.genre=article


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