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hal.structure.identifierImagerie moléculaire et fonctionnelle: de la physiologie à la thérapie
dc.contributor.authorQUESSON, Bruno
hal.structure.identifierLaboratoire de Dynamique des Fluides [DynFluid]
dc.contributor.authorMERLE, Mathilde
hal.structure.identifierSAP AG [Germany]
dc.contributor.authorKÖHLER, Max
hal.structure.identifierImagerie moléculaire et fonctionnelle: de la physiologie à la thérapie
dc.contributor.authorMOUGENOT, Charles
hal.structure.identifierImagerie moléculaire et fonctionnelle: de la physiologie à la thérapie
dc.contributor.authorROUJOL, Sebastien
hal.structure.identifierInstitut de Mathématiques de Bordeaux [IMB]
dc.contributor.authorDENIS DE SENNEVILLE, Baudouin
hal.structure.identifierImagerie moléculaire et fonctionnelle: de la physiologie à la thérapie
dc.contributor.authorMOONEN, Chrit
dc.date.accessioned2024-04-04T03:10:24Z
dc.date.available2024-04-04T03:10:24Z
dc.date.issued2010
dc.identifier.issn0094-2405
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/193686
dc.description.abstractEnHigh Intensity Focused Ultrasound (HIFU) seems promising for the non invasive treatment of liver tumors. However, the presence of ribs in the HIFU beam path remains problematic since they can create adverse effects (skin burns) by absorption and reflection of the incident beam. This paperpresents a method based on Magnetic Resonance (MR) Imaging for the identification of the ribs in the HIFU beam and selection of the transducer elements to deactivate. The ribs were visualized on anatomical images acquired prior to heating and manually segmented. The resulting regions of interest surrounding the ribs were projected on the transducer surface by ray tracing from the focal point to select the transducer elements to deactivate. The method was validated ex vivo and in vivo in pig liver during breathing under multi slice real-time MR thermometry, using the proton resonant frequency shift method. Ex vivo and in vivo temperature data showed that the temperature increase near the ribs was important when HIFU sonications were performed with all the elements active, whereas the temperature was reduced with deactivation of the transducer elements located in front of the ribs. The temperature at the focal point was similar with and without deactivation of the transducer elements, indicative of the absence of heat efficacy loss with the proposed technique. This method is simple, rapid and reliable and allows to perform intercostal HIFU ablation while sparing the ribs.
dc.language.isoen
dc.publisherAmerican Association of Physicists in Medicine
dc.subject.enHIFU
dc.subject.enMR thermometry 1
dc.subject.enliver
dc.subject.enRib
dc.title.enA method for MRI guidance of intercostal high intensity focused ultrasound ablation in the liver
dc.typeArticle de revue
dc.identifier.doi10.1118/1.3413996
dc.subject.halSciences de l'ingénieur [physics]/Traitement du signal et de l'image
dc.subject.halSciences du Vivant [q-bio]/Ingénierie biomédicale/Imagerie
bordeaux.journalMedical Physics
bordeaux.page2533–2540
bordeaux.volume37
bordeaux.hal.laboratoriesInstitut de Mathématiques de Bordeaux (IMB) - UMR 5251*
bordeaux.issue6
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierhal-01503914
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-01503914v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Medical%20Physics&rft.date=2010&rft.volume=37&rft.issue=6&rft.spage=2533%E2%80%932540&rft.epage=2533%E2%80%932540&rft.eissn=0094-2405&rft.issn=0094-2405&rft.au=QUESSON,%20Bruno&MERLE,%20Mathilde&K%C3%96HLER,%20Max&MOUGENOT,%20Charles&ROUJOL,%20Sebastien&rft.genre=article


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