Afficher la notice abrégée

Three-Dimensional Measurement Of hepatocellular carcinoma Ablation Zones And Margins For Predicting Local Tumor Progression

hal.structure.identifierHôpital Saint-André
dc.contributor.authorHOCQUELET, Arnaud
hal.structure.identifierHôpital Saint-André
dc.contributor.authorTRILLAUD, Hervé
hal.structure.identifierService d'imagerie diagnostique et interventionelle
dc.contributor.authorFRULIO, Nora
hal.structure.identifierHôpital Saint-André
dc.contributor.authorPAPADOPOULOS, Panteleimon
hal.structure.identifierHôpital Saint-André
dc.contributor.authorBALAGEAS, P.
hal.structure.identifierHôpital Saint-André
dc.contributor.authorSALUT, C.
hal.structure.identifierHôpital Saint-André
dc.contributor.authorMEYER, Marie
hal.structure.identifierHôpital Saint-André
dc.contributor.authorBLANC, Jean-Frédéric
hal.structure.identifierHôpital Haut-Lévêque [CHU Bordeaux]
dc.contributor.authorMONTAUDON, Michel
hal.structure.identifierInstitut de Mathématiques de Bordeaux [IMB]
dc.contributor.authorDENIS DE SENNEVILLE, Baudouin
dc.date.accessioned2024-04-04T03:07:02Z
dc.date.available2024-04-04T03:07:02Z
dc.date.issued2016
dc.identifier.issn1051-0443
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/193398
dc.description.abstractEnPurpose: To propose a postprocessing technique that measures tumor surface with insufficient ablative margins (r 5 mm) on magnetic resonance (MR) imaging to predict local tumor progression (LTP) following radiofrequency (RF) ablation.Materials and Methods: A diagnostic method is proposed based on measurement of tumor surface with a margin r 5 mm on MR imaging. The postprocessing technique includes fully automatic registration of pre-and post–RF ablation MR imaging, a semiautomatic segmentation of pre–RF ablation tumor and post–RF ablation volume, and a subsequent calculation of the three-dimensional exposed tumor surface area. The ability to use this surface margin r 5 mm to predict local recurrence at 2 years was then tested on 16 patients with cirrhosis who were treated by RF ablation with a margin r 5 mm in 2012: eight with LTP matched according to tumor size and number and α-fetoprotein level versus eight without local recurrence. Results: The error of estimated tumor surface with a margin r 5 mm was less than 12%.Results of a log-rank test showed that patients with a tumor surface area 4 425 mm 2 had a 2-year LTP rate of 77.5%, compared with 25% for patients with a tumor surface area r 425 mm 2 (P ¼ .018).Conclusions: This proof-of-concept study proposes an accurate and reliable postprocessing technique to estimate tumor surface with insufficient ablative margins, and underscores the potential usefulness of tumor surface with a margin r 5 mm to stratify patients with HCC treated by RF ablation according to their risk of LTP.
dc.language.isoen
dc.publisherElsevier
dc.title.enThree-Dimensional Measurement Of hepatocellular carcinoma Ablation Zones And Margins For Predicting Local Tumor Progression
dc.typeArticle de revue
dc.identifier.doi10.1016/j.jvir.2016.02.031
dc.subject.halSciences du Vivant [q-bio]/Ingénierie biomédicale/Imagerie
dc.subject.halSciences de l'ingénieur [physics]/Traitement du signal et de l'image
dc.subject.halSciences du Vivant [q-bio]/Cancer
bordeaux.journalJVIR: Journal of Vascular and Interventional Radiology
bordeaux.page1038-1045.e2
bordeaux.volume27
bordeaux.hal.laboratoriesInstitut de Mathématiques de Bordeaux (IMB) - UMR 5251*
bordeaux.issue7
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierhal-01312564
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-01312564v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=JVIR:%20Journal%20of%20Vascular%20and%20Interventional%20Radiology&rft.date=2016&rft.volume=27&rft.issue=7&rft.spage=1038-1045.e2&rft.epage=1038-1045.e2&rft.eissn=1051-0443&rft.issn=1051-0443&rft.au=HOCQUELET,%20Arnaud&TRILLAUD,%20Herv%C3%A9&FRULIO,%20Nora&PAPADOPOULOS,%20Panteleimon&BALAGEAS,%20P.&rft.genre=article


Fichier(s) constituant ce document

FichiersTailleFormatVue

Il n'y a pas de fichiers associés à ce document.

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée