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hal.structure.identifierModélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
hal.structure.identifierUniversité de Bordeaux [UB]
hal.structure.identifierIHU-LIRYC
dc.contributor.authorCOUDIÈRE, Yves
hal.structure.identifierModélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
hal.structure.identifierUniversité de Bordeaux [UB]
hal.structure.identifierIHU-LIRYC
hal.structure.identifierDépartement de Biologie Computationnelle - Department of Computational Biology
dc.contributor.authorDAVIDOVIĆ, Anđela
hal.structure.identifierModélisation Mathématique pour l'Oncologie [MONC]
hal.structure.identifierUniversité de Bordeaux [UB]
dc.contributor.authorPOIGNARD, Clair
dc.date.accessioned2024-04-04T02:59:09Z
dc.date.available2024-04-04T02:59:09Z
dc.date.issued2019-10-12
dc.identifier.issn1937-1632
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/192720
dc.description.abstractEnIn this paper we study how mesoscopic heterogeneities affect electrical signal propagation in cardiac tissue. The standard model used in cardiac electrophysiology is a bidomain model-a system of degenerate parabolic PDEs, coupled with a set of ODEs, representing the ionic behviour of the cardiac cells. We assume that the heterogeneities in the tissue are periodically distributed diffusive regions, that are significantly larger than a cardiac cell. These regions represent the fibrotic tissue, collagen or fat, that is electrically passive. We give a mathematical setting of the model. Using semigroup theory we prove that such model has a uniformly bounded solution. Finally, we use two-scale convergence to find the limit problem that represents the average behviour of the electrical signal in this setting.
dc.description.sponsorshipModèles numériques haute résolution de l'électrophysiologie cardiaque - ANR-13-MONU-0004
dc.description.sponsorshipL'Institut de Rythmologie et modélisation Cardiaque - ANR-10-IAHU-0004
dc.language.isoen
dc.publisherAmerican Institute of Mathematical Sciences
dc.subject.enCardiac electrophysiology
dc.subject.enSemigroup theory
dc.subject.enBido-main model
dc.subject.enHomogenisation in periodic media
dc.subject.enDegenerate parabolic systems
dc.subject.enStructural heterogeneities
dc.title.enModified bidomain model with passive periodic heterogeneities
dc.typeArticle de revue
dc.identifier.doi10.3934/dcdss.2020126
dc.subject.halMathématiques [math]/Equations aux dérivées partielles [math.AP]
bordeaux.journalDiscrete and Continuous Dynamical Systems - Series S
bordeaux.hal.laboratoriesInstitut de Mathématiques de Bordeaux (IMB) - UMR 5251*
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierhal-02363470
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-02363470v1
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