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Transmural APD gradient synchronizes repolarization in the human left ventricular wall

hal.structure.identifierThe George Washington University [GW]
dc.contributor.authorBOUKENS, Bastiaan
hal.structure.identifierWashington University in Saint Louis [WUSTL]
dc.contributor.authorSULKIN, Matthew
hal.structure.identifierThe George Washington University [GW]
dc.contributor.authorGLOSCHAT, Chris
hal.structure.identifierImperial College London
dc.contributor.authorNG, Fu Siong
hal.structure.identifierModélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
dc.contributor.authorVIGMOND, Edward
hal.structure.identifierThe George Washington University [GW]
hal.structure.identifierIHU-LIRYC
dc.contributor.authorEFIMOV, Igor
dc.date.accessioned2024-04-04T02:51:07Z
dc.date.available2024-04-04T02:51:07Z
dc.date.issued2015-09-16
dc.identifier.issn0008-6363
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/191968
dc.description.abstractEnThe duration and morphology of the T wave predict risk for ventricular fibrillation. A transmural gradient in action potential duration (APD) in the ventricular wall has been suggested to underlie the T wave in humans. We hypothesize that the transmural gradient in APD compensates for the normal endocardium-to-epicardium activation sequence and synchronizes repolarization in the human ventricular wall.
dc.language.isoen
dc.publisherOxford University Press (OUP)
dc.subject.enHuman
dc.subject.enOptical mapping
dc.subject.enRepolarization
dc.subject.enT wave
dc.title.enTransmural APD gradient synchronizes repolarization in the human left ventricular wall
dc.typeArticle de revue
dc.identifier.doi10.1093/cvr/cvv202
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologie
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologie/Cardiologie et système cardiovasculaire
bordeaux.journalCardiovascular Research
bordeaux.page188-196
bordeaux.volume108
bordeaux.hal.laboratoriesInstitut de Mathématiques de Bordeaux (IMB) - UMR 5251*
bordeaux.issue1
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierhal-02886265
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-02886265v1
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