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Acceptance Factors for In-Hospital Pharmacist Interventions in Daily Practice: A Retrospective Study

hal.structure.identifierInstitut de Mathématiques de Bordeaux [IMB]
dc.contributor.authorDURAND, Amaury
hal.structure.identifierCHU Rouen
dc.contributor.authorGILLIBERT, André
dc.contributor.authorMEMBRE, Sophie
hal.structure.identifierCHU Amiens-Picardie
dc.contributor.authorMONDET, Lisa
hal.structure.identifierMécanismes physiopathologiques et conséquences des calcifications cardiovasculaires - UR UPJV 7517 [MP3CV]
hal.structure.identifierCHU Amiens-Picardie
dc.contributor.authorLENGLET, Aurélie
hal.structure.identifierMécanismes physiopathologiques et conséquences des calcifications cardiovasculaires - UR UPJV 7517 [MP3CV]
dc.contributor.authorMARY, Aurelien
dc.date.accessioned2024-04-04T02:33:51Z
dc.date.available2024-04-04T02:33:51Z
dc.date.issued2022
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/190512
dc.description.abstractEnIntroduction: Performing pharmacist interventions (PIs) during the medication review helps to improve the quality of care. The acceptance by the physician of these PIs is a good indicator of the quality of this clinical pharmacy activity. The objective of this study was to determine, in the Amiens-Picardie teaching hospital (France), factors of acceptance in a variable environment of activity (central pharmacy, in the care units, computer assisted).Methods: All PIs transcribed by pharmacists on the Act-IP (c) site between November 2018 and April 2019 were analyzed using a complementary search in patient records. The environment, type, and clinical impact on patient health of each PI was collected. Linear mixed-effects models with a random pharmacist intercept were used to investigate the relationship between PI modalities and their chance of being accepted.Results: A total of 3,100 PIs were traced, of which 2,930 had been followed over time. Of these, 2,930 PIs, 1,504 (51.3%) were performed by a postgraduate pharmacist and 1,426 (48.7%) by a pharmacy resident, 1,623 (55.4%) were performed by verbal exchange, 455 (15.5%) by telephone, 846 (28.9%) by computer software, and 6 (0.2%) by paper. The clinical impact on patient health was major for 976 PIs (33.3%) and vital for 26 PIs (0.9%). According to the Anatomical Therapeutic Chemical Classification (ATC), they were mainly related to anti-infectives (30.3%), the nervous system (18.7%), and blood and blood-forming organs (17.3%). In total, 2,415 PIs (82.4%) were accepted. According to the multivariate model, a PI was more often accepted when it was transmitted orally rather than by software (+27.7%, 95% CI: +23.2 to +32.1%) and when it was transmitted to a medical resident rather than a postgraduate physician (+4.4%, 95% CI: 1.2-7.6%). In these cases, there was a major rather than a moderate clinical impact on patient health (+4.3%, 95% CI: +1.1-+7.6%).Conclusion: This study highlights the importance of the quality of the exchange with the prescriber and the prioritization of high-risk interventions as key points of medication review to improve rate of pharmacist interventions accepted by physician.
dc.language.isoen
dc.subject.enclinical pharmacy
dc.subject.enquality of care
dc.subject.encontact method
dc.subject.enpharmacist interventions
dc.subject.enmedication review
dc.title.enAcceptance Factors for In-Hospital Pharmacist Interventions in Daily Practice: A Retrospective Study
dc.typeArticle de revue
dc.identifier.doi10.3389/fphar.2022.811289
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologie
bordeaux.journalFRONTIERS IN PHARMACOLOGY
bordeaux.volume13
bordeaux.hal.laboratoriesInstitut de Mathématiques de Bordeaux (IMB) - UMR 5251*
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierhal-04139786
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-04139786v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=FRONTIERS%20IN%20PHARMACOLOGY&rft.date=2022&rft.volume=13&rft.au=DURAND,%20Amaury&GILLIBERT,%20Andr%C3%A9&MEMBRE,%20Sophie&MONDET,%20Lisa&LENGLET,%20Aur%C3%A9lie&rft.genre=article


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