Mostrar el registro sencillo del ítem
Control of extended-spectrum β-lactamase-producing Enterobacteriaceae nosocomial acquisition in an intensive care unit: A time series regression analysis.
| hal.structure.identifier | Pharmaco-Épidémiologie des Produits de Santé [PEPS] | |
| dc.contributor.author | BOYER, Alexandre | |
| hal.structure.identifier | Institut de Mathématiques de Bordeaux [IMB] | |
| dc.contributor.author | COUALLIER, Vincent | |
| hal.structure.identifier | CHU Bordeaux | |
| dc.contributor.author | CLOUZEAU, Benjamin | |
| hal.structure.identifier | CHU Bordeaux | |
| dc.contributor.author | LASHERAS, Agnes | |
| hal.structure.identifier | Microbiologie Fondamentale et Pathogénicité [MFP] | |
| dc.contributor.author | M'ZALI, Fatima | |
| hal.structure.identifier | Microbiologie Fondamentale et Pathogénicité [MFP] | |
| dc.contributor.author | KANN, Michael | |
| hal.structure.identifier | Pharmaco-Épidémiologie des Produits de Santé [PEPS] | |
| dc.contributor.author | ROGUES, Anne-Marie | |
| hal.structure.identifier | Microbiologie Fondamentale et Pathogénicité [MFP] | |
| dc.contributor.author | GRUSON, Didier | |
| dc.date.accessioned | 2024-04-04T02:32:25Z | |
| dc.date.available | 2024-04-04T02:32:25Z | |
| dc.date.issued | 2015-12-01 | |
| dc.identifier.issn | 0196-6553 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/190385 | |
| dc.description.abstractEn | This study was undertaken to determine the temporal relationship between implementation of different interventions in an intensive care unit (ICU) and control of endemic nosocomial acquisition of extended-spectrum β-lactamase Enterobacteriaceae (ESBLE). This was a prospective observational study with time-series analysis of the monthly incidence of ESBLE and its predictors. In November 2007, after a 14-month baseline period, an intervention consisting of restriction of third-generation cephalosporins (3 GC) and increased use of alcohol-based hand rubs was implemented. In January 2008, an increased health care worker (HCW):patient ratio was also implemented. In March 2010, the ICU was closed, and patients were moved to a clean ICU. The first intervention resulted in global reduction in 3 GC and increased use of alcohol-based hand rub. A significant change in ESBLE incidence was observed in a full segmented univariate regression analysis (mean change in level, -0.91 ± 0.19; P < .0001). After ICU closure, there was a dramatic reduction in ESBLE acquisition. According to the multivariate model, the ICU closure was the main protective factor. Before ICU closure, an increase in the HCW:patient ratio of 0.1 point tended to be associated with a decreased risk of ESBLE acquisition (relative risk, 0.28; 95% confidence interval, 0.06-1.25; P = .09). This study shows that ICU closure was associated with, but not necessarily the reason for, control of ESBLE cross-transmission in a nonoutbreak setting. Environmental ESBE sources may play a role in cross-transmission. | |
| dc.language.iso | en | |
| dc.publisher | Elsevier | |
| dc.subject.en | Cross Infection | |
| dc.subject.en | Enterobacteriaceae | |
| dc.subject.en | Enterobacteriaceae Infections | |
| dc.subject.en | Humans | |
| dc.subject.en | Infection Control | |
| dc.subject.en | Intensive Care Units | |
| dc.subject.en | Middle Aged | |
| dc.subject.en | Prospective Studies | |
| dc.subject.en | Regression Analysis | |
| dc.subject.en | beta-Lactamases | |
| dc.title.en | Control of extended-spectrum β-lactamase-producing Enterobacteriaceae nosocomial acquisition in an intensive care unit: A time series regression analysis. | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1016/j.ajic.2015.07.026 | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Microbiologie et Parasitologie | |
| bordeaux.journal | American Journal of Infection Control | |
| bordeaux.page | 1296-301 | |
| bordeaux.volume | 43 | |
| bordeaux.hal.laboratories | Institut de Mathématiques de Bordeaux (IMB) - UMR 5251 | * |
| bordeaux.issue | 12 | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.institution | CNRS | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-04297344 | |
| hal.version | 1 | |
| hal.popular | non | |
| hal.audience | Internationale | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-04297344v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=American%20Journal%20of%20Infection%20Control&rft.date=2015-12-01&rft.volume=43&rft.issue=12&rft.spage=1296-301&rft.epage=1296-301&rft.eissn=0196-6553&rft.issn=0196-6553&rft.au=BOYER,%20Alexandre&COUALLIER,%20Vincent&CLOUZEAU,%20Benjamin&LASHERAS,%20Agnes&M'ZALI,%20Fatima&rft.genre=article |
Archivos en el ítem
| Archivos | Tamaño | Formato | Ver |
|---|---|---|---|
|
No hay archivos asociados a este ítem. |
|||