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Measured and Simulated P Waves in Normal Subjects Reflect Complex Atrial Anatomy

hal.structure.identifierModélisation et calculs pour l'électrophysiologie cardiaque [CARMEN]
hal.structure.identifierInstitut de Mathématiques de Bordeaux [IMB]
hal.structure.identifierIHU-LIRYC
hal.structure.identifierUniversity of Lugano
dc.contributor.authorPOTSE, Mark
hal.structure.identifierMaastricht University [Maastricht]
dc.contributor.authorLANKVELD, Theo
hal.structure.identifierMaastricht University [Maastricht]
dc.contributor.authorZEEMERING, Stef
hal.structure.identifierFontys Hogeschool Toegepaste Natuurwetenschappen = Fontys University of Applied Sciences [FONTYS]
dc.contributor.authorKUIJPERS, Nico
hal.structure.identifierMaastricht University [Maastricht]
dc.contributor.authorSCHOTTEN, Ulrich
dc.date.accessioned2024-04-04T02:21:02Z
dc.date.available2024-04-04T02:21:02Z
dc.date.issued2013-08-01
dc.date.conference2013-08-07
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/189536
dc.description.abstractEnIntroduction: The shape of the P wave can yield important information about the substrate of atrial fibrillation (AF). On the routine 12-lead ECG, P waves have a smooth appearance. Computer simulation studies with realistic atrial models have shown highly complex P-wave shapes with details that were linked to structural features of the atria. We assessed the true shape of the P wave in control subjects. Methods: We recorded 184-channel high-resolution ECGs in 6 healthy volunteers and averaged over 300 beats for each. Beats were aligned on their P waves. Alignment was based on a compound signal of all 184 channels to reduce the effect of noise on alignment. In addition, 12-lead ECGs were simulated using a single patient-tailored heart-torso model with detailed atrial anatomy. Results: Averaging reduced the noise level to less than 2 microvolt (uV) peak-to-peak. Signal features of a few uV amplitude and less than 5 milliseconds (ms) duration could be reliably distinguished. Measured P waves had 4 to 5 separate peaks that were reproducible between recordings. Simulated P waves demonstrated similar complexity, which was related to structural discontinuities in the computer model of the atria. Conclusions: The true shape of the P wave is very irregular and reflects the complex anatomy of the atria. High-resolution electrocardiography is necessary to reliably assess P-wave shape.
dc.language.isoen
dc.publisherElsevier
dc.source.titleJournal of Electrocardiology
dc.title.enMeasured and Simulated P Waves in Normal Subjects Reflect Complex Atrial Anatomy
dc.typeCommunication dans un congrès
dc.identifier.doi10.1016/j.jelectrocard.2013.05.067
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologie/Cardiologie et système cardiovasculaire
dc.description.sponsorshipEuropeOptimization of noninvasive assessment of the substrate for atrial fibrillation
bordeaux.pagee18
bordeaux.volume46
bordeaux.hal.laboratoriesInstitut de Mathématiques de Bordeaux (IMB) - UMR 5251*
bordeaux.issue4
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.conference.titleICE 2013 - 40th International Congress on Electrocardiology
bordeaux.countryGB
bordeaux.title.proceedingJournal of Electrocardiology
bordeaux.conference.cityGlasgow
bordeaux.peerReviewedoui
hal.identifierhal-00906507
hal.version1
hal.invitednon
hal.proceedingsnon
hal.conference.end2013-08-10
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00906507v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.btitle=Journal%20of%20Electrocardiology&rft.date=2013-08-01&rft.volume=46&rft.issue=4&rft.spage=e18&rft.epage=e18&rft.au=POTSE,%20Mark&LANKVELD,%20Theo&ZEEMERING,%20Stef&KUIJPERS,%20Nico&SCHOTTEN,%20Ulrich&rft.genre=unknown


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