Circulating endothelial cells in pathophysiology.
| dc.rights.license | open | en_US |
| hal.structure.identifier | Biologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases | |
| dc.contributor.author | BRETT, Victor-Emmanuel | |
| hal.structure.identifier | Laboratoire d'Immunologie [Hôpital de la Conception - APHM] | |
| dc.contributor.author | DIGNAT-GEORGE, Francoise | |
| hal.structure.identifier | Biologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases | |
| dc.contributor.author | JAMES, Chloe | |
| dc.date.accessioned | 2024-03-25T15:35:42Z | |
| dc.date.available | 2024-03-25T15:35:42Z | |
| dc.date.issued | 2024-05-01 | |
| dc.identifier.issn | 1531-7048 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/188964 | |
| dc.description.abstractEn | The purpose of this review is to synthesize recent insights into the roles and importance of circulating endothelial cells (CECs) as indicators of the severity, progression, and prognosis of vascular-related diseases. Recent studies have identified elevated counts of CECs in pathological conditions, notably inflammatory or cardiovascular diseases such as acute myocardial infarction and heart failure, underscoring their potential as sensitive indicators of disease. Furthermore, the rise in CEC levels in cancer patients, particularly with disease advancement, points to their role in cancer-associated angiogenesis and response to treatment. This review underscores the evolving significance of CECs as markers for evaluating the gravity and advancement of diseases with vascular injury, including cardiovascular diseases, cancer, inflammatory conditions, and thromboembolic events. These last years, efforts made to standardize flow cytometry detection of CEC and the development of highly sensitive techniques to isolate, quantify or phenotype rare cells open promising avenues for clinical application. This may yield extensive knowledge regarding the mechanisms by which endothelial cells contribute to a variety of vascular-related disorders and their clinical value as emerging biomarkers. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Humans | |
| dc.subject.en | Endothelial Cells | |
| dc.subject.en | Biomarkers | |
| dc.subject.en | Myocardial Infarction | |
| dc.subject.en | Vascular Diseases | |
| dc.subject.en | Neoplasms | |
| dc.subject.en | Flow Cytometry | |
| dc.title.en | Circulating endothelial cells in pathophysiology. | |
| dc.title.alternative | Curr Opin Hematol | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1097/MOH.0000000000000814 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Médecine humaine et pathologie | en_US |
| dc.identifier.pubmed | 38362895 | en_US |
| bordeaux.journal | Current Opinion in Hematology | en_US |
| bordeaux.page | 148-154 | en_US |
| bordeaux.volume | 31 | en_US |
| bordeaux.hal.laboratories | Biologie des maladies cardiovasculaires (BMC) - UMR 1034 | en_US |
| bordeaux.issue | 3 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | pubmed | |
| hal.identifier | hal-04520469 | |
| hal.version | 1 | |
| hal.date.transferred | 2024-03-25T15:35:44Z | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | true | |
| workflow.import.source | pubmed | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Current%20Opinion%20in%20Hematology&rft.date=2024-05-01&rft.volume=31&rft.issue=3&rft.spage=148-154&rft.epage=148-154&rft.eissn=1531-7048&rft.issn=1531-7048&rft.au=BRETT,%20Victor-Emmanuel&DIGNAT-GEORGE,%20Francoise&JAMES,%20Chloe&rft.genre=article |
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