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Psychoactive substance intoxication leading to general hospital admission in young and middle-aged people during and after the first lockdown

dc.rights.licenseopenen_US
dc.contributor.authorPERINO, Justine
ORCID: 0000-0003-0039-0734
IDREF: 254309690
dc.contributor.authorRAMAROSON, Hanta
dc.contributor.authorONG, Nathalie
dc.contributor.authorLANCELOT, Victoire
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBEZIN, Julien
ORCID: 0000-0002-2568-1928
IDREF: 181595710
dc.contributor.authorGILLERON, Veronique
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDAVELUY, Amelie
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorTOURNIER, Marie
dc.date.accessioned2024-01-16T15:45:47Z
dc.date.available2024-01-16T15:45:47Z
dc.date.issued2023-11-22
dc.identifier.issn1958-5578en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/187279
dc.description.abstractEnINTRODUCTION: Incidence of hospitalisations related to psychoactive substance (H-PS) intoxication has been strongly decreased during the coronavirus disease 2019 (COVID-19) pandemic especially in young adult and French region of Nouvelle-Aquitaine was mostly concerned. This study aimed to describe (i) the incidence of H-PS in Bordeaux teaching hospital during and after the first 2020 lockdown in adults aged 18-29 years or 30+ then (ii) their characteristics specifically associated with the pandemic period by comparing 2020 with 2017-2019 baseline period. MATERIAL AND METHODS: This historical cohort study was conducted in adults admitted to the Bordeaux teaching hospital with main or associated diagnosis codes of intoxication with benzodiazepine, methadone, buprenorphine, codeine, morphine, heroin, cocaine, ecstasy and alcohol. Data were collected locally through the discharge database. Incidence and characteristics of H-PS were described according to patients' age, in 2020 before (01/01-16/03), during (17/03-10/05), and after the first lockdown (11/05-31/07). RESULTS: Among the 5,824 stays included over the study period, PS most involved were alcohol and benzodiazepines. Compared to baseline, the decrease in H-PS's incidence was more important in young adults (-40%; n(baseline)=450) in comparison to those aged 30+ (-18%; n(baseline)=1,101) during the pandemic period, especially during the lockdown compared to 2017 (-59%; n(2017)=145 vs. -35%; n(2017)=166) with far decrease in alcohol and ecstasy intoxications. Seriousness of hospitalisation indications was increased regardless of age during the pandemic. Particularly in young adults, the proportion of suicides attempts increased during lockdown compared to the baseline period (almost 50% vs. 29%) and the period after lockdown was associated with 1.7 more-time road accident increased and 3 more-time fights compared with pre-lockdown period. DISCUSSION/CONCLUSION: The period following lockdown should be considered at risk H-PS due to accident. Recreational use of alcohol and ecstasy could be a target for minimize serious consequences associated to PS use in young adult.
dc.language.isoENen_US
dc.title.enPsychoactive substance intoxication leading to general hospital admission in young and middle-aged people during and after the first lockdown
dc.title.alternativeTherapieen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.therap.2023.10.017en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed38036330en_US
bordeaux.journalTherapiesen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamAHEAD_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04398425
hal.version1
hal.date.transferred2024-01-18T07:39:22Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Therapies&rft.date=2023-11-22&rft.eissn=1958-5578&rft.issn=1958-5578&rft.au=PERINO,%20Justine&RAMAROSON,%20Hanta&ONG,%20Nathalie&LANCELOT,%20Victoire&BEZIN,%20Julien&rft.genre=article


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