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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorTABUE TEGUO, Maturin
ORCID: 0000-0002-1211-5660
IDREF: 175400768
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorVILLENEUVE, Roxane
dc.contributor.authorHELENE-PELAGE, Jeannie
dc.contributor.authorCESARI, Matteo
dc.contributor.authorCHOVINO, Jordane
dc.contributor.authorBOIRE, Axelle
dc.contributor.authorDRAMÉ, Moustapha
dc.contributor.authorSIMO-TABUÉ, Nadine
dc.contributor.authorBOUCAUD-MAITRE, Denis
dc.date.accessioned2023-10-17T09:33:14Z
dc.date.available2023-10-17T09:33:14Z
dc.date.issued2023-05-11
dc.identifier.issn1937-8688en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/184452
dc.description.abstractEnthe increasing prevalence of polypharmacy in the older population could lead to inappropriate storage of medicines at home. Since polypharmacy is associated with frailty, the main objective of the Karukera Study of Aging - Drug Storage (KASADS) study was to investigate the association between drug storage and frailty. If such an association exists, drug storage could be a simple tool for the identification of medication vulnerability by non-medical staff in the elderly. observational, cross-sectional study in community-dwelling older adults (>65 years old). Drug storage was defined as any drug in excess compared to a medical prescription, any unused and/or expired drug, or any drug without a medical prescription. Frailty was measured with the Study of Osteoporotic Fractures (SOF) scale, and polypharmacy was defined as a prescription of at least 5 drugs. Bivariate and multivariate analyses were performed to study the associations between drugs storage, frailty, and polypharmacy. during the study period (01/10/2019 to 15/03/2020), 115 elderly people were interviewed in their own homes. The average age was 76.0 ± 7.8 years old. Seventy-two percent of the participants met the criteria for polypharmacy and 30.4% were prefrail/frail. They stored an average of 14.7 ± 18.2 boxes. Drug storage was associated with polypharmacy (17.5 boxes versus 10.0; p=0.031) but not with frailty (15.6 versus 14.3; p=0.724). In multivariate analysis, drug storage was associated with not having a school degree (OR: 1.78; 95%CI: 1.13-2.79), suffering from dyslipidemia (OR: 2.00; 95% CI: 1.28-3.17) and suffering from cognitive disorders evaluated by the Mini Mental State Examination (MMSE) score (OR: 1.10; 95%CI: 1.02-1.17). drug storage was not significantly associated with frailty. Nevertheless, it was associated with polypharmacy and other medical outcomes, and could therefore represent a new area for research in geriatrics and pharmacy.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enHumans
dc.subject.enAged
dc.subject.enAged
dc.subject.en80 and over
dc.subject.enFrailty
dc.subject.enFrail Elderly
dc.subject.enPolypharmacy
dc.subject.enCross-Sectional Studies
dc.subject.enInappropriate Prescribing
dc.title.enDrug storage, polypharmacy and frailty syndrome in older people: an observational study
dc.title.alternativePan Afr Med Jen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.11604/pamj.2023.45.29.32636en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed37521760en_US
bordeaux.journalThe Pan African Medical Journalen_US
bordeaux.page29en_US
bordeaux.volume45en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamACTIVEen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-04245762
hal.version1
hal.date.transferred2023-10-17T09:33:17Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=The%20Pan%20African%20Medical%20Journal&rft.date=2023-05-11&rft.volume=45&rft.spage=29&rft.epage=29&rft.eissn=1937-8688&rft.issn=1937-8688&rft.au=TABUE%20TEGUO,%20Maturin&VILLENEUVE,%20Roxane&HELENE-PELAGE,%20Jeannie&CESARI,%20Matteo&CHOVINO,%20Jordane&rft.genre=article


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