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dc.rights.licenseopenen_US
dc.contributor.authorREED, Claire
dc.contributor.authorCORTESE, Samuele
dc.contributor.authorLARSSON, Henrik
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorGALERA, Cedric
ORCID: 0000-0003-0549-9608
IDREF: 110034007
dc.contributor.authorCOTTON, Joanne
dc.contributor.authorBRANDT, Valerie
dc.date.accessioned2023-10-04T13:46:20Z
dc.date.available2023-10-04T13:46:20Z
dc.date.issued2023-07-03
dc.identifier.issn1527-5418en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/184319
dc.description.abstractEnAlthough evidence suggests significant cross-sectional relationships between attention-deficit/hyperactivity disorder (ADHD) and several physical health conditions, less is known about their longitudinal associations. We investigated the cumulative effect of childhood physical health conditions on ADHD symptoms at age 17 years, controlling for environmental factors, ADHD medication status, and ADHD symptoms at age 3 years. Using Millennium Cohort Study data (weighted n = 8,059), we assessed whether 4 physical health clusters (sensory, neurological, atopic, and cardio-metabolic) were associated with scores on the ADHD subscale from the Strengths and Difficulties Questionnaire at age 17 years. Environmental factors were grouped into 5 cumulative risk indices: prenatal, perinatal, postnatal environment, postnatal maternal well-being, and sociodemographic factors. Regression analyses determined whether each physical health cluster was associated with ADHD score while controlling for environmental factors, ADHD medication, and earlier symptoms. Sensory, neurological, and cardio-metabolic clusters were all significantly associated with ADHD symptoms (β range = 0.04-0.09, p < .001). The overall model explained 2% of the variance. This rose to 21% (ΔR = 0.06) after adjusting for confounders. The sensory (β = 0.06) and neurological (β = 0.06) clusters remained significant (R = 0.21, ΔR = 0.06), but the cardio-metabolic cluster was no longer a significant predictor. Sensory or neurological conditions in childhood were associated with higher ADHD symptoms aged 17 after adjustment of confounders. This was not the case for atopic or cardio-metabolic conditions. These findings have implications for the care of children with sensory/neurological conditions and future research examining ADHD etiopathophysiology.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enADHD
dc.subject.enADHD medication
dc.subject.enEnvironmental factors
dc.subject.enPhysical health
dc.title.enLongitudinal Associations Between Physical Health Conditions in Childhood and Attention-Deficit/Hyperactivity Disorder Symptoms at Age 17 Years.
dc.title.alternativeJ Am Acad Child Adolesc Psychiatryen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.jaac.2023.06.016en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed37406771en_US
dc.description.sponsorshipEuropeHorizon 2020 research and innovation programmeen_US
bordeaux.journalJournal of the American Academy of Child and Adolescent Psychiatryen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamHEALTHYen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-04228553
hal.version1
hal.date.transferred2023-10-04T13:46:22Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&amp;rft_val_fmt=info:ofi/fmt:kev:mtx:journal&amp;rft.jtitle=Journal%20of%20the%20American%20Academy%20of%20Child%20and%20Adolescent%20Psychiatry&amp;rft.date=2023-07-03&amp;rft.eissn=1527-5418&amp;rft.issn=1527-5418&amp;rft.au=REED,%20Claire&amp;CORTESE,%20Samuele&amp;LARSSON,%20Henrik&amp;GALERA,%20Cedric&amp;COTTON,%20Joanne&amp;rft.genre=article


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