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The effect of the 7R allele at the DRD4 locus on risk tolerance is independent of background risk in Senegalese fishermen

hal.structure.identifierCentre de Recherche en Économie et Statistique [CREST]
hal.structure.identifierUniversity of Chicago
dc.contributor.authorCLOCHARD, Gwen-Jirō
hal.structure.identifierUniversité Gaston Berger de Saint-Louis Sénégal [UGB]
dc.contributor.authorMBENGUE, Aby
hal.structure.identifierInstitut de génétique humaine [IGH]
hal.structure.identifierInstitut des Sciences de l'Evolution de Montpellier [UMR ISEM]
dc.contributor.authorMETTLING, Clément
hal.structure.identifierUniversité Gaston Berger de Saint-Louis Sénégal [UGB]
dc.contributor.authorDIOUF, Birane
hal.structure.identifierInstitut des Sciences de l'Evolution de Montpellier [UMR ISEM]
dc.contributor.authorFAURIE, Charlotte
hal.structure.identifierUniversité Alioune Diop de Bambey [UADB]
dc.contributor.authorSENE, Omar
hal.structure.identifierBiodiversité, Gènes & Communautés [BioGeCo]
dc.contributor.authorCHANCEREL, Emilie
hal.structure.identifierBiodiversité, Gènes & Communautés [BioGeCo]
dc.contributor.authorGUICHOUX, Erwan
hal.structure.identifierCentre de Recherche en Économie et Statistique [CREST]
dc.contributor.authorHOLLARD, Guillaume
hal.structure.identifierInstitut des Sciences de l'Evolution de Montpellier [UMR ISEM]
dc.contributor.authorRAYMOND, Michel
hal.structure.identifierCentre d'Economie de l'Environnement - Montpellier [CEE-M]
dc.contributor.authorWILLINGER, Marc
dc.date.issued2023
dc.identifier.issn2045-2322
dc.description.abstractEnIt has been shown that living in risky environments, as well as having a risky occupation, can moderate risk-tolerance. Despite the involvement of dopamine in the expectation of reward described by neurobiologists, a GWAS study was not able to demonstrate a genetic contribution of genes involved in the dopaminergic pathway in risk attitudes and gene candidate studies gave contrasting results. We test the possibility that a genetic effect of the DRD4-7R allele in risk-taking behavior could be modulated by environmental factors. We show that the increase in risk-tolerance due to the 7R allele is independent of the environmental risk in two populations in Northern Senegal, one of which is exposed to a very high risk due to dangerous fishing.
dc.description.sponsorshipIdex Paris-Saclay - ANR-11-IDEX-0003
dc.description.sponsorshipRéguler l'économie au service de la société
dc.language.isoen
dc.publisherNature Publishing Group
dc.rights.urihttp://creativecommons.org/licenses/by/
dc.subject.enLocal adaptation
dc.subject.endopamine receptor
dc.subject.enpopulation genetics
dc.subject.eneconomic games
dc.subject.enbehaviour
dc.subject.enLocal adaptation
dc.title.enThe effect of the 7R allele at the DRD4 locus on risk tolerance is independent of background risk in Senegalese fishermen
dc.typeArticle de revue
dc.identifier.doi10.1038/s41598-022-27002-3
dc.subject.halSciences de l'Homme et Société/Anthropologie biologique
dc.subject.halSciences du Vivant [q-bio]/Génétique/Génétique humaine
dc.subject.halSciences du Vivant [q-bio]/Génétique/Génétique des populations [q-bio.PE]
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]/Psychologie et comportements
dc.subject.halSciences de l'Homme et Société/Economies et finances
dc.subject.jelZ - Other Special Topics/Z.Z1 - Cultural Economics • Economic Sociology • Economic Anthropology/Z.Z1.Z13 - Economic Sociology • Economic Anthropology • Social and Economic Stratification
bordeaux.journalScientific Reports
bordeaux.page622
bordeaux.volume13
bordeaux.issue1
bordeaux.peerReviewedoui
hal.identifierhal-03954770
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-03954770v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Scientific%20Reports&rft.date=2023&rft.volume=13&rft.issue=1&rft.spage=622&rft.epage=622&rft.eissn=2045-2322&rft.issn=2045-2322&rft.au=CLOCHARD,%20Gwen-Jir%C5%8D&MBENGUE,%20Aby&METTLING,%20Cl%C3%A9ment&DIOUF,%20Birane&FAURIE,%20Charlotte&rft.genre=article


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