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A thorough investigation of the bifactor model of psychopathology in a representative birth cohort: Testing internal and predictive validity to inform models of comorbidity

dc.rights.licenseopenen_US
dc.contributor.authorPOCUCA, Nina
dc.contributor.authorGEOFFROY, Marie-Claude
dc.contributor.authorPAQUIN, Stephane
dc.contributor.authorARCHAMBAULT, Kim
dc.contributor.authorSEGUIN, Jean R.
dc.contributor.authorPARENT, Sophie
dc.contributor.authorBOIVIN, Michel
dc.contributor.authorTREMBLAY, Richard E.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorCOTE, Sylvana
ORCID: 0000-0001-7944-0647
dc.contributor.authorCASTELLANOS-RYAN, Natalie
dc.date.accessioned2023-04-19T08:41:19Z
dc.date.available2023-04-19T08:41:19Z
dc.date.issued2023-02
dc.identifier.issn2769-755X (Electronic) 2769-7541 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/173089
dc.description.abstractEnThis study used symptom dimensions reflecting DSM-V internalizing, externalizing, eating disorders, and substance use (SU) and related problems to thoroughly investigate the structure of psychopathology in mid-adolescence (15 and 17 years, N = 1,515, 52% female). Compared to other hierarchical configurations (unidimensional, correlated factors, or higher-order model), a bifactor model of psychopathology wherein all first-order symptom dimensions loaded onto a second-order general psychopathology factor (P factor) and one of three, second-order specific internalizing, externalizing, or SU factors, best captured the structure of the psychopathology in mid-adolescence. This bifactor model was then used to predict several distinct mental health disorders and alcohol use disorder (AUD) at 20 years, via a structural equation model (SEM). The P factor (bifactor model) was associated with all but one outcome (suicidal ideation without an attempt), at 20 years. Controlling for the P factor, there were no additional, positive, temporal cross-associations (i.e., between mental health (mid-adolescence) and AUD at 20 years, or between SU (mid-adolescence) and mental health problems at 20 years). These results are bolstered by findings from a well-fitting correlated factors model. Namely, when mid-adolescent psychopathology was modeled using an adjusted correlated factors model, associations with outcomes at 20 years were largely masked, with no significant partial, temporal cross-associations. Thus, collectively, findings indicate that comorbidity between SU and mental health in youth may be largely attributable to an underlying liability to experience both problems (i.e., P factor). Ultimately, results support targeting the common liability to psychopathology in the prevention of later mental health problems and AUD.
dc.language.isoENen_US
dc.title.enA thorough investigation of the bifactor model of psychopathology in a representative birth cohort: Testing internal and predictive validity to inform models of comorbidity
dc.title.alternativeJ Psychopathol Clin Scien_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1037/abn0000816en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed36808956en_US
bordeaux.journalJournal of Psychopathology and Clinical Scienceen_US
bordeaux.page123-134en_US
bordeaux.volume132en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue2en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamHEALTHY_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04074036
hal.version1
hal.date.transferred2023-04-19T08:41:21Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
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