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Integrating services for HIV and multidrug-resistant tuberculosis: A global cross-sectional survey among ART clinics in low- and middle-income countries
| dc.rights.license | open | en_US |
| dc.contributor.author | ZURCHER, Kathrin | |
| dc.contributor.author | COX, Samyra R. | |
| dc.contributor.author | BALLIF, Marie | |
| dc.contributor.author | ENANE, Leslie A. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | MARCY, Olivier | |
| dc.contributor.author | YOTEBIENG, Marcel | |
| dc.contributor.author | REUBENSON, Gary | |
| dc.contributor.author | IMSANGUAN, Worarat | |
| dc.contributor.author | OTERO, Larissa | |
| dc.contributor.author | SURYAVANSHI, Nishi | |
| dc.contributor.author | DUDA, Stephany N. | |
| dc.contributor.author | EGGER, Matthias | |
| dc.contributor.author | TORNHEIM, Jeffrey A. | |
| dc.contributor.author | FENNER, Lukas | |
| dc.date.accessioned | 2023-03-14T13:35:17Z | |
| dc.date.available | 2023-03-14T13:35:17Z | |
| dc.date.issued | 2022-03-01 | |
| dc.identifier.issn | 2767-3375 (Electronic) 2767-3375 (Linking) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/172297 | |
| dc.description.abstractEn | Tuberculosis (TB) is the leading cause of death among PLHIV and multidrug-resistant-TB (MDR-TB) is associated with high mortality. We examined the management for adult PLHIV coinfected with MDR-TB at ART clinics in lower income countries. Between 2019 and 2020, we conducted a cross-sectional survey at 29 ART clinics in high TB burden countries within the global IeDEA network. We used structured questionnaires to collect clinic-level data on the TB and HIV services and the availability of diagnostic tools and treatment for MDR-TB. Of 29 ART clinics, 25 (86%) were in urban areas and 19 (66%) were tertiary care clinics. Integrated HIV-TB services were reported at 25 (86%) ART clinics for pan-susceptible TB, and 14 (48%) clinics reported full MDR-TB services on-site, i.e. drug susceptibility testing [DST] and MDR-TB treatment. Some form of DST was available on-site at 22 (76%) clinics, while the remainder referred testing off-site. On-site DST for second-line drugs was available at 9 (31%) clinics. MDR-TB treatment was delivered on-site at 15 (52%) clinics, with 10 individualizing treatment based on DST results and five using standardized regimens alone. Bedaquiline was routinely available at 5 (17%) clinics and delamanid at 3 (10%) clinics. Although most ART clinics reported having integrated HIV and TB services, few had fully integrated MDR-TB services. There is a continued need for increased access to diagnostic and treatment options for MDR-TB patients and better integration of MDR-TB services into the HIV care continuum. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.title.en | Integrating services for HIV and multidrug-resistant tuberculosis: A global cross-sectional survey among ART clinics in low- and middle-income countries | |
| dc.title.alternative | PLOS Glob Public Health | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1371/journal.pgph.0000180 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 36778080 | en_US |
| bordeaux.journal | PLOS Global Public Health | en_US |
| bordeaux.volume | 2 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.issue | 3 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | GHiGS_BPH | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-04028614 | |
| hal.version | 1 | |
| hal.date.transferred | 2023-03-14T13:35:32Z | |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=PLOS%20Global%20Public%20Health&rft.date=2022-03-01&rft.volume=2&rft.issue=3&rft.eissn=2767-3375%20(Electronic)%202767-3375%20(Linking)&rft.issn=2767-3375%20(Electronic)%202767-3375%20(Linking)&rft.au=ZURCHER,%20Kathrin&COX,%20Samyra%20R.&BALLIF,%20Marie&ENANE,%20Leslie%20A.&MARCY,%20Olivier&rft.genre=article |
