Afficher la notice abrégée

dc.rights.licenseopenen_US
hal.structure.identifierIBIO - Plateforme de bio-imagerie en sciences médicales
dc.contributor.authorFUKUTOMI, Hikaru
dc.contributor.authorHAMITOUCHE, Lydia
hal.structure.identifierIBIO - Plateforme de bio-imagerie en sciences médicales
dc.contributor.authorYAMAMOTO, Takayuki
hal.structure.identifierIBIO - Plateforme de bio-imagerie en sciences médicales
dc.contributor.authorDENAT, Laurent
dc.contributor.authorZHANG, Lijun
dc.contributor.authorZHANG, Bei
dc.contributor.authorPREVOST, Valentin
dc.contributor.authorTRIAIRE, Bruno
hal.structure.identifierIBIO - Plateforme de bio-imagerie en sciences médicales
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorDOUSSET, Vincent
dc.contributor.authorBARREAU, Xavier
hal.structure.identifierIBIO - Plateforme de bio-imagerie en sciences médicales
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorTOURDIAS, Thomas
dc.date.accessioned2023-03-13T15:28:50Z
dc.date.available2023-03-13T15:28:50Z
dc.date.issued2022-05
dc.identifier.issn0938-7994en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/172278
dc.description.abstractEnObjectives: 3D-fluid attenuation inversion recovery (FLAIR) collected 4 h after intravenous gadolinium injection can delineate the perilymphatic space (PLS) from the endolymphatic space (ELS) to capture endolymphatic hydrops, the pathological counterpart of Ménière’s disease. We aimed to optimize visualization of such inner ear internal anatomy using 3D-FLAIR without injection. Methods: 3D-FLAIR signal from different fluid compartments such as PLS and ELS was first simulated. Then, twenty-two healthy subjects were scanned at 3.0-T MRI with non-injected 3D-FLAIR using variable T2 preparations (T2Preps) (OFF, 200, 400, and 600 ms) and variable inversion times (TIs) (from 224 to 5000 ms) and different resolutions (1.0 × 1.0 × 1.5, 0.6 × 0.6 × 0.8, and 0.6 × 0.6 × 0.6 mm3). The relative contrast between PLS and ELS and the visibility of the saccule and utricle were assessed. Additionally, non-injected 3D-FLAIR with the optimal setting was tested in a Ménière patient and compared with gadolinium-injected 3D-FLAIR. Results: The PLS and ELS were differentiated when T2Prep was used but not without. The relative contrast was larger with T2Prep at 400 ms than at 200 or 600 ms (0.72 ± 0.22 vs. 0.44 ± 0.11, p = 0.019; and 0.72 ± 0.22 vs. 0.46 ± 0.28, p = 0.034, respectively). The saccule and utricle were best delineated in 87. % cases with T2Prep = 400 and TI = 2100 ms at the highest resolution. Visualization of the saccule and utricle in the optimized non-injected 3D-FLAIR was similar to conventional injected 3D-FLAIR in a patient. Conclusions: Combining a specific T2Prep and TI in non-injected 3D-FLAIR could separate PLS and ELS and even the saccule and utricle, paving the way toward future application to diagnose Ménière’s disease. Key Points: • MRI can capture the internal anatomy of inner ear without injection of contrast media. • Specific parameters consisting of a T2 preparation of 400 ms and an inversion time of 2100 ms must be used to visualize the saccule and utricle on non-injected 3D-FLAIR. © 2021, The Author(s), under exclusive licence to European Society of Radiology.
dc.language.isoENen_US
dc.subject.enEar vestibule
dc.subject.enEndolymphatic hydrops
dc.subject.enGadolinium
dc.subject.enMagnetic resonance imaging
dc.subject.enMeniere disease
dc.title.enVisualization of the saccule and utricle with non-contrast-enhanced FLAIR sequences
dc.title.alternativeEur Radiolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s00330-021-08403-wen_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed34928414en_US
bordeaux.journalEuropean Radiologyen_US
bordeaux.page3532-3540en_US
bordeaux.volume32en_US
bordeaux.hal.laboratoriesNeurocentre Magendie - U1215en_US
bordeaux.issue5en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamRelations glie-neuroneen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04027135
hal.version1
hal.date.transferred2023-03-13T15:28:54Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=European%20Radiology&rft.date=2022-05&rft.volume=32&rft.issue=5&rft.spage=3532-3540&rft.epage=3532-3540&rft.eissn=0938-7994&rft.issn=0938-7994&rft.au=FUKUTOMI,%20Hikaru&HAMITOUCHE,%20Lydia&YAMAMOTO,%20Takayuki&DENAT,%20Laurent&ZHANG,%20Lijun&rft.genre=article


Fichier(s) constituant ce document

FichiersTailleFormatVue

Il n'y a pas de fichiers associés à ce document.

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée