Impact of Albumin Assays in the Diagnosis of Malnutrition in Hemodialysis Patients: A Cohort Study.
dc.rights.license | open | en_US |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | RAMI ARAB, Lila | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | DABERNAT, Sandrine | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | BOUTIN, Julian | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | BORDENAVE, Chloé | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | KARMANI, Malek | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | COLOMBIÈS, Brigitte | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | DELMAS, Yahsou | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | DE-LA-FAILLE, Renaud | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | DE PRÉCIGOUT, Valérie | |
hal.structure.identifier | Biologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases | |
dc.contributor.author | RUBIN, Sébastien | |
hal.structure.identifier | CHU de Bordeaux Pellegrin [Bordeaux] | |
dc.contributor.author | MOREAU, Karine | |
hal.structure.identifier | Biologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases | |
dc.contributor.author | BATS, Marie-Lise | |
dc.date.accessioned | 2023-03-03T10:41:27Z | |
dc.date.available | 2023-03-03T10:41:27Z | |
dc.date.issued | 2022-10-19 | |
dc.identifier.issn | 1532-8503 | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/172153 | |
dc.description.abstractEn | In hemodialysis (HD) patients, malnutrition should be diagnosed by several assessment tools including a plasma albumin concentration of less than 3.8 g/dL or 3.5 g/dL using bromocresol green or immunonephelometry (IN), respectively. However, albumin measurement is not yet standardized and two alternative methods are also commonly used in laboratories: bromocresol purple (BCP) and immunoturbidimetry (IT). This study aimed to revisit the hypoalbuminemia thresholds for BCP and IT, in HD patients. Plasma albumin was measured by the four analytical methods during the monthly HD nutritional assessment of 103 prospectively included patients. Significant differences in albumin levels were observed in HD patients depending on the method used. Using BCP or IT with the cut-off at 3.5 g/dL (determined for the general population) we obtained 33% and 9.7% of false hypoalbuminemia in comparison to IN (mean bias of -0.4 g/dL and -0.065 g/dL, respectively). The best hypoalbuminemia threshold for BCP was 3.05 g/dL and 3.4 g/dL for IT. Twenty percent of HD patients were classified as malnourished when albumin was determined by IN. Similar rates were obtained using the new hypoalbuminemia cut-offs for BCP (18.5%) and IT (19.5%). To avoid nutritional misclassification of HD patients, we should adjust hypoalbuminemia thresholds when BCP or IT methods are used in laboratories. | |
dc.language.iso | EN | en_US |
dc.subject.en | Albumin; analytical method; cut-off; hemodialysis; malnutrition | |
dc.title.en | Impact of Albumin Assays in the Diagnosis of Malnutrition in Hemodialysis Patients: A Cohort Study. | |
dc.title.alternative | J Ren Nutr | en_US |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1053/j.jrn.2022.10.001 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Médecine humaine et pathologie | en_US |
dc.identifier.pubmed | 36270483 | en_US |
bordeaux.journal | Journal of Renal Nutrition | en_US |
bordeaux.hal.laboratories | Biologie des maladies cardiovasculaires (BMC) - UMR 1034 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | INSERM | en_US |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
bordeaux.import.source | pubmed | |
hal.identifier | hal-04013128 | |
hal.version | 1 | |
hal.date.transferred | 2023-03-03T10:41:34Z | |
hal.export | true | |
workflow.import.source | pubmed | |
dc.rights.cc | CC BY-NC-ND | en_US |
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