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dc.rights.licenseopenen_US
dc.contributor.authorLEROY, Victoire
dc.contributor.authorCHEN, Yaohua
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBOUTELOUP, Vincent
dc.contributor.authorSKROBALA, Emilie
dc.contributor.authorPUISIEUX, Francois
dc.contributor.authorFOUGERE, Bertrand
dc.date.accessioned2023-02-22T14:00:04Z
dc.date.available2023-02-22T14:00:04Z
dc.date.issued2023-01-19
dc.identifier.issn1538-9375 (Electronic) 1525-8610 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/172058
dc.description.abstractEnOBJECTIVES: Identifying risk factors for falls can improve outcomes in older patients without cognitive decline. Yet this has not been demonstrated in older people with mild cognitive impairment (MCI). We therefore sought to better identify risk factors for falls in this particular group. DESIGN: The analysis was conducted on the MEMENTO cohort, which is a large, French, prospective cohort. SETTING AND PARTICIPANTS: We included older people (>65 years old) with MCI (defined from neuropsychological scores) and a Short Physical Performance Battery (SPPB) score at baseline. METHODS: Fallers were defined as participants having fallen at least once during the study's 2-year follow-up period. We compared clinical, neuropsychological, and biological data at baseline in fallers vs nonfallers. Additional analyses were performed on the following subgroups: women, men, people aged ≥75 years. RESULTS: Of the 1416 people included in our study, 194 (13.5%) fell at least once. A bivariate analysis showed that fallers were older, predominantly women, less independent in activities of daily living, and more apathetic. Fallers performed less well in executive function, balance, and gait tests. In a multivariable analysis, only age, gender, the number of limitations in instrumental activities of daily living, and living alone were significantly associated with falls. In a multivariable analysis of the subgroup of oldest patients and of the subgroup of men, executive function was significantly worse in fallers than in nonfallers. CONCLUSION AND IMPLICATIONS: Our results demonstrate that easily attainable risk factors can be used to identify individuals with MCI with a higher risk of falls and for whom prevention could be beneficial. Future studies are needed to further evaluate the role of mild executive dysfunction in certain subgroups, such as men and oldest patients.
dc.language.isoENen_US
dc.subject.enFalls
dc.subject.enMild cognitive impairment
dc.subject.enRisk factors
dc.subject.enOlder adults
dc.subject.enMemory clinic
dc.title.enWhat Tools Can We Use to Screen for Fall Risk in Older Patients With Mild Cognitive Impairment? Findings From the MEMENTO Cohort
dc.title.alternativeJ Am Med Dir Assocen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.jamda.2022.12.020en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed36682387en_US
bordeaux.journalJournal of the American Medical Directors Associationen_US
bordeaux.page1028-1034
bordeaux.volume24
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue7
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamPHARES_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04000813
hal.version1
hal.date.transferred2023-02-22T14:00:18Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
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