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Incidence of retinal detachment, macular edema, and ocular hypertension after Nd:YAG capsulotomy: a population-based nationwide study - the FreYAG2 study
| dc.rights.license | open | en_US |
| dc.contributor.author | DOT, Corinne | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | SCHWEITZER, Cedric
ORCID: 0000-0002-2162-9479 IDREF: 133631583 | |
| dc.contributor.author | LABBE, Antoine | |
| dc.contributor.author | LIGNEREUX, Francois | |
| dc.contributor.author | ROZOT, Pascal | |
| dc.contributor.author | GOGUILLOT, Melanie | |
| dc.contributor.author | BUGNARD, Francoise | |
| dc.contributor.author | BREZIN, Antoine P. | |
| dc.date.accessioned | 2023-02-15T09:40:44Z | |
| dc.date.available | 2023-02-15T09:40:44Z | |
| dc.date.issued | 2023-05 | |
| dc.identifier.issn | 1549-4713 (Electronic) 0161-6420 (Linking) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/171956 | |
| dc.description.abstractEn | OBJECTIVE: To estimate the incidence and assess the risk factors associated with 3 adverse events (AE) of interest after Nd:YAG posterior capsulotomy (Nd:YAG-caps): ocular hypertension (OHT), macular edema (ME) and retinal detachment (RD). DESIGN: Observational cohort study using a nationwide claims database. PARTICIPANTS: Adults who underwent Nd:YAG-caps between 2014 and 2017, with no ocular disease history in the year before. METHODS: Nd:YAG-caps patients were identified using data from the French national 1/97(th) representative sample and followed-up for 12 months post-Nd:YAG-caps. The time to AE was assessed using Kaplan-Meier method. Factors associated with AE were assessed using Cox models. MAIN OUTCOME MEASURES: Nd:YAG-caps epidemiology; patients' characteristics; proportion of patients with AE; Hazard ratios (HRs) associated to variables identified as factors associated with AEs of interest, overall and by AE. RESULTS: During the study period, 6,210 patients with Nd:YAG-caps were identified (7,958 procedures). The mean age (±sd) at Nd:YAG-caps was 75.0 (±10.3) years. The 3-month and 12-month overall AE rates (≥1 AE of interest [OHT, ME, RD]) were 8.6% and 13.3%, respectively. Among patients with ≥1 AE of interest, 68.4% of AEs occurred within 3 months post-Nd:YAG-caps. Three-month rates were similar for OHT and ME (≈5%). RD rate remained ≤0.5% over the entire follow-up. Cox models showed that patients with Nd:YAG-caps performed within 1-year post-cataract surgery were of higher risk of AE than those with later Nd:YAG-caps (HR 1.314 [1.034-1.669], p=0.0256). Diabetic patients were more at risk of OHT (HR 1.233 [1.005-1.513], p=0.0448) and ME (HR 1.810 [1.446-2.266], p=<.0001) than non-diabetic ones. Patients with Nd:YAG-caps within 1-year post-cataract surgery were more at risk of ME (HR 1.500 [1.087-2.070], p=0.0137). Patients with Nd:YAG-caps performed between the first- and second-year post-cataract were more at risk of OHT than patients with later Nd:YAG-caps (HR 1.429 [1.185-1.723], p=0.0002). CONCLUSIONS: Based on a national claims database, OHT and ME were the most frequent AE of interest post-Nd:YAG-caps, mainly observed within the first 3 months post-procedure, highlighting the need for a close follow-up during this period or a delayed capsulotomy if possible. Diabetes and an early Nd:YAG-caps post-cataract surgery were among the main drivers for AE occurrence. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Adverse events | |
| dc.subject.en | Cataract | |
| dc.subject.en | Database | |
| dc.subject.en | Data claims | |
| dc.subject.en | Nd:YAG | |
| dc.subject.en | Ophthalmology | |
| dc.subject.en | Risk factors | |
| dc.title.en | Incidence of retinal detachment, macular edema, and ocular hypertension after Nd:YAG capsulotomy: a population-based nationwide study - the FreYAG2 study | |
| dc.title.alternative | Ophthalmology | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.ophtha.2022.12.022 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 36581227 | en_US |
| bordeaux.journal | Ophthalmology: Journal of The American Academy of Ophthalmology | en_US |
| bordeaux.page | 478-487 | |
| bordeaux.volume | 130 | |
| bordeaux.volume | 478-487 | |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.issue | 5 | |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | LEHA_BPH | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03990005 | |
| hal.version | 1 | |
| hal.date.transferred | 2023-02-15T09:40:57Z | |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Ophthalmology:%20Journal%20of%20The%20American%20Academy%20of%20Ophthalmology&rft.date=2023-05&rft.volume=130&478-487&rft.issue=5&rft.spage=478-487&rft.epage=478-487&rft.eissn=1549-4713%20(Electronic)%200161-6420%20(Linking)&rft.issn=1549-4713%20(Electronic)%200161-6420%20(Linking)&rft.au=DOT,%20Corinne&SCHWEITZER,%20Cedric&LABBE,%20Antoine&LIGNEREUX,%20Francois&ROZOT,%20Pascal&rft.genre=article |
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