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dc.rights.licenseopenen_US
dc.contributor.authorCREUZOT-GARCHER, Catherine
dc.contributor.authorMASSIN, Pascale
dc.contributor.authorSROUR, Mayer
dc.contributor.authorBAUDIN, Florian
dc.contributor.authorDOT, Corinne
dc.contributor.authorNGHIEM-BUFFET, Sylvia
dc.contributor.authorGIRMENS, Jean-Francois
dc.contributor.authorCOLLIN, Cedric
dc.contributor.authorPONTHIEUX, Anne
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDELCOURT, Cécile
ORCID: 0000-0002-2099-0481
IDREF: 035105291
dc.date.accessioned2022-12-15T10:16:16Z
dc.date.available2022-12-15T10:16:16Z
dc.date.issued2022-10-28
dc.identifier.issn1999-4923 (Print) 1999-4923 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/171531
dc.description.abstractEnAIM: LANDSCAPE aimed to estimate the annual incidence and prevalence of treated diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) between 2008 and 2018. METHODS: This French nationwide observational study used data from the French National Health Insurance Databases covering 99% of the French population. Data about healthcare consumption were used to identify adults treated with anti-VEGFs or dexamethasone implants (for DME) and with pan-retinal photocoagulation (for PDR). All French patients newly treated between 2008 and 2018 were included. Incidence and prevalence of treated DME and PDR were estimated for the age-matched general population and the population with diabetes in France. Sociodemographic characteristics and medical history were described in both populations. RESULTS: We identified 53,584 treated DME patients and 127,273 treated PDR patients between 2008 and 2018, and 11,901 DME and 11,996 PDR new incident patients in 2018. The treated DME incidence in 2018 was 2.5 per 10,000 in the general population and 37.3 per 10,000 in the population with diabetes. Prevalence in 2018 was 9.5 and 143.7 per 10,000 in the respective populations. Treated PDR incidence in 2018 was 2.3 per 10,000 in the general population and 31.2 per 10,000 in the population with diabetes. Prevalence in 2018 was 19.9 and 270.3 per 10,000 in the respective populations. Incidence and prevalence were not age-dependent. Incidence of treated PDR incidence was relatively stable from 2008-2018. Incidence of treated DME incidence rose from 2012-2018, probably due to widening access to newly available treatments, such as anti-VEGFs. CONCLUSIONS: We provide exhaustive nationwide data on the incidence and prevalence of treated diabetic ocular complications in France over a 10-year period.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enDiabetic macular edema
dc.subject.enDiabetic retinopathy
dc.subject.enIncidence
dc.subject.enPrevalence
dc.subject.enFrance
dc.subject.enDrug consumption
dc.subject.enNationwide study
dc.title.enEpidemiology of Treated Diabetes Ocular Complications in France 2008-2018-The LANDSCAPE French Nationwide Study
dc.typeArticle de revueen_US
dc.identifier.doi10.3390/pharmaceutics14112330en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed36365148en_US
bordeaux.journalPharmaceuticsen_US
bordeaux.volume14en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue11en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamLEHA_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Pharmaceutics&rft.date=2022-10-28&rft.volume=14&rft.issue=11&rft.eissn=1999-4923%20(Print)%201999-4923%20(Linking)&rft.issn=1999-4923%20(Print)%201999-4923%20(Linking)&rft.au=CREUZOT-GARCHER,%20Catherine&MASSIN,%20Pascale&SROUR,%20Mayer&BAUDIN,%20Florian&DOT,%20Corinne&rft.genre=article


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