Afficher la notice abrégée

Trends in the relation between hyperglycemia correction and active Charcot neuroarthropathy: results from the EPICHAR study

dc.rights.licenseopenen_US
dc.contributor.authorDARDARI, Dured
dc.contributor.authorSCHULDINER, Sophie
dc.contributor.authorJULIEN, Carole-Anne
dc.contributor.authorHA VAN, Georges
dc.contributor.authorM'BEMBA, Jocelyne
dc.contributor.authorBOURGEON, Muriel
dc.contributor.authorSULTAN, Ariane
dc.contributor.authorLEPEUT, Marc
dc.contributor.authorGRANDPERRET-VAUTHIER, Sylvie
dc.contributor.authorBAUDOUX, Florence
dc.contributor.authorFRANCOIS, Maud
dc.contributor.authorCLAVEL, Sylvaine
dc.contributor.authorMARTINI, Jacques
dc.contributor.authorVOUILLARMET, Julien
dc.contributor.authorMICHON, Paul
dc.contributor.authorMORET, Myriam
dc.contributor.authorMONNIER, Arnaud
dc.contributor.authorCHINGAN-MARTINO, Vaneva
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorRIGALLEAU, Vincent
dc.contributor.authorDUMONT, Isabelle
dc.contributor.authorKESSLER, Laurence
dc.contributor.authorSTIFII, Ionela
dc.contributor.authorBOUILLET, Benjamin
dc.contributor.authorBONNIN, Pierre
dc.contributor.authorLEMOINE, Amal
dc.contributor.authorDA COSTA CORREIA, Enrique
dc.contributor.authorFARAILL, Marie Martine Bonello
dc.contributor.authorMULLER, Marie
dc.contributor.authorCAZAUBIEL, Marie
dc.contributor.authorZEMMACHE, Mohammed Zakarya
dc.contributor.authorHARTEMANN, Agnes
dc.date.accessioned2022-10-31T13:44:00Z
dc.date.available2022-10-31T13:44:00Z
dc.date.issued2022-09
dc.identifier.issn2052-4897 (Electronic) 2052-4897 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/170175
dc.description.abstractEnIntroduction The pathophysiology of Charcot neuroarthropathy (CN) remains unclear. There are a number of hypotheses but these are not exclusive. In its clinical presentation, this complication intersects with the semiology of diabetic-induced neuropathy, such as peripheral hypervascularization and the appearance of arteriovenous shunt. The EPICHAR study is as yet an unpublished cohort of people living with diabetes complicated by CN (in active or chronic phase). Based on the findings of the EPICHAR study, this study aimed to investigate whether a reduction in the rate of hyperglycemia accompanies the onset of an active phase of CN. Research design and methods Hemoglobin A1c (HbA1c) levels were assessed 3 months (M3) and 6 months (M6) before the diagnosis of active CN (M0). Results 103 patients living with diabetes and presenting active CN were included between January and December 2019 from the 31 centers participating in this study (30 in France and 1 in Belgium). The mean age of the participants was 60.2 +/- 12.2 years; the vast majority were men (71.8%) living with type 2 diabetes (75.5%). Mean HbA1c levels significantly declined between M6 (median 7.70; 01, 03: 7.00, 8.55) and M3 (median 7.65; 01, 03: 6.90, 8.50) (p=0.012), as well as between M6 and M0 (median 7.40; 01, 03: 6.50, 8.50) (p=0.014). No significant difference was found between M3 and M0 (p=0.072). Conclusions A significant reduction in HbA1c levels seems to accompany the onset of the active phase of CN.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/us/*
dc.title.enTrends in the relation between hyperglycemia correction and active Charcot neuroarthropathy: results from the EPICHAR study
dc.typeArticle de revueen_US
dc.identifier.doi10.1136/bmjdrc-2021-002380en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed36215101en_US
bordeaux.journalBMJ Open Diabetes Research & Careen_US
bordeaux.volume10en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue5en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamLEHA_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=BMJ%20Open%20Diabetes%20Research%20&%20Care&rft.date=2022-09&rft.volume=10&rft.issue=5&rft.eissn=2052-4897%20(Electronic)%202052-4897%20(Linking)&rft.issn=2052-4897%20(Electronic)%202052-4897%20(Linking)&rft.au=DARDARI,%20Dured&SCHULDINER,%20Sophie&JULIEN,%20Carole-Anne&HA%20VAN,%20Georges&M'BEMBA,%20Jocelyne&rft.genre=article


Fichier(s) constituant ce document

Thumbnail
Nom:
BPH_BMJOPRC_2022_Dardari.pdf
Taille:
293.9Ko
Format:
PDF
Voir/Ouvrir
Thumbnail
Nom:
license_rdf
Taille:
920octets
Format:
application/rdf+xml
Voir/Ouvrir

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée