Afficher la notice abrégée

Trajectories of sleep duration and timing before dementia: a 14-year follow-up study

dc.rights.licenseopenen_US
dc.contributor.authorCAVAILLES, Clemence
dc.contributor.authorCARRIERE, Isabelle
dc.contributor.authorWAGNER, Maude
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDARTIGUES, Jean-Francois
ORCID: 0000-0001-9482-5529
IDREF: 058586105
dc.contributor.authorBERR, Claudine
dc.contributor.authorDAUVILLIERS, Yves
dc.contributor.authorJAUSSENT, Isabelle
dc.date.accessioned2022-10-29T10:51:49Z
dc.date.available2022-10-29T10:51:49Z
dc.date.issued2022-08-02
dc.identifier.issn1468-2834 (Electronic) 0002-0729 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/170162
dc.description.abstractEnBACKGROUND: given the complex relationship between sleep and neurodegenerative processes, it is important to examine whether changes in sleep patterns occur prior or close to dementia onset. OBJECTIVE: to examine the relationship between sleep parameters and dementia incidence and, to characterize trajectories of sleep patterns before dementia diagnosis. DESIGN: a 14-year longitudinal study including a nested case-control study. SETTING: the French Three-City Study. SUBJECTS: overall, 1,749 cognitively healthy participants (>/=65 years) for the longitudinal study and, 182 incident dementia cases and 719 controls matched by sex, age and educational level for the case-control study. METHODS: dementia cases were assessed at each visit and self-reported sleep parameters at baseline, 2, 8, 10, 12 and 14 years. Cox models were used to estimate the risk of dementia associated with baseline sleep parameters (sleep duration, time in bed (TIB), sleep timing, sleepiness and insomnia). Latent-process mixed models were performed to compare sleep trajectories according to the case-control status. RESULTS: long baseline nighttime and 24-h sleep durations (>/=9 h) as well as being persistent or becoming long sleepers during follow-up were associated with dementia incidence. Trajectories of sleep durations and TIB showed faster increases in cases compared with controls up to 12 years before dementia. The mean differences [95%CI] for 24-h sleep duration between cases and controls were: 0.27 h [0.01;0.52], 0.34 [0.09;0.58] and 0.67 [0.44;0.90] at -12, -8 and -2 years, respectively. Bedtime trajectories showed an earlier bedtime in cases up to -8 years. CONCLUSION: long sleep duration and earlier bedtime may impact dementia incidence.
dc.language.isoENen_US
dc.title.enTrajectories of sleep duration and timing before dementia: a 14-year follow-up study
dc.typeArticle de revueen_US
dc.identifier.doi10.1093/ageing/afac186en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed35977152en_US
bordeaux.journalAge and Ageingen_US
bordeaux.volume51en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue8en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamACTIVE_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03834317
hal.version1
hal.date.transferred2022-10-29T10:51:50Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Age%20and%20Ageing&rft.date=2022-08-02&rft.volume=51&rft.issue=8&rft.eissn=1468-2834%20(Electronic)%200002-0729%20(Linking)&rft.issn=1468-2834%20(Electronic)%200002-0729%20(Linking)&rft.au=CAVAILLES,%20Clemence&CARRIERE,%20Isabelle&WAGNER,%20Maude&DARTIGUES,%20Jean-Francois&BERR,%20Claudine&rft.genre=article


Fichier(s) constituant ce document

FichiersTailleFormatVue

Il n'y a pas de fichiers associés à ce document.

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée