Mostrar el registro sencillo del ítem

Pleural plaques and risk of lung cancer in workers formerly occupationally exposed to asbestos: extension of follow-up

dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorGALLET, Justine
hal.structure.identifierCentre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
dc.contributor.authorLAURENT, Francois
dc.contributor.authorPARIS, Christophe
dc.contributor.authorCLIN, Benedicte
dc.contributor.authorGISLARD, Antoine
dc.contributor.authorTHAON, Isabelle
dc.contributor.authorCHAMMINGS, Soizick
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorGRAMOND, Celine
dc.contributor.authorOGIER, Guy
dc.contributor.authorFERRETTI, Gilbert
dc.contributor.authorANDUJAR, Pascal
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBROCHARD, Patrick
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDELVA, Fleur
dc.contributor.authorPAIRON, Jean-Claude
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLACOURT, Aude
dc.date.accessioned2022-10-27T09:24:28Z
dc.date.available2022-10-27T09:24:28Z
dc.date.issued2022-08-03
dc.identifier.issn1470-7926 (Electronic) 1351-0711 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/170122
dc.description.abstractEnBACKGROUND: Occupational asbestos exposure is associated with pleural plaques (PP), a benign disease often seen as a marker of past exposure to asbestos and lung cancer. The association between these two diseases has not been formally proved, the aim of this study was to evaluate this association in the asbestos-related disease cohort (ARDCO) cohort. METHODS: ARDCO is a French multicentric cohort including workers formerly occupationally exposed to asbestos from 2003 to 2005. CT scan was performed to diagnose PP with double reading and lung cancer (incidence and mortality) was followed through health insurance data and death certificates. Cox models were used to estimate the association between PP and lung cancer adjusting for occupational asbestos exposure (represented by cumulative exposure index, time since first exposure and time since last exposure) and smoking status. RESULTS: A total of 176 cases (of 5050 subjects) and 88 deaths (of 4938 subjects) of lung cancer were recorded. Smoking status was identified as an effect modifier. Lung cancer incidence and mortality were significantly associated with PP only in non-smokers, respectively, HR=3.13 (95% CI 1.04 to 9.35) and HR=16.83 (95% CI 1.87 to 151.24) after adjustment for age, occupational asbestos exposure and smoking status. CONCLUSIONS: ARDCO study was the first to study this association considering equal asbestos exposure, and more specifically, our study is the first to test smoking as an effect modifier, so comparison with scientific literature is difficult. Our results seem to consolidate the hypothesis that PP may be an independent risk factor for lung cancer but they must be interpreted with caution.
dc.language.isoENen_US
dc.title.enPleural plaques and risk of lung cancer in workers formerly occupationally exposed to asbestos: extension of follow-up
dc.typeArticle de revueen_US
dc.identifier.doi10.1136/oemed-2022-108337en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed35922129en_US
bordeaux.journalOccupational and Environmental Medicineen_US
bordeaux.volume79en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue10en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamEPICENE_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDMinistère du Travail, de l’Emploi, de la Formation Professionnelle et du Dialogue Socialen_US
bordeaux.identifier.funderIDAgence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travailen_US
hal.identifierhal-03788410
hal.version1
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Occupational%20and%20Environmental%20Medicine&rft.date=2022-08-03&rft.volume=79&rft.issue=10&rft.eissn=1470-7926%20(Electronic)%201351-0711%20(Linking)&rft.issn=1470-7926%20(Electronic)%201351-0711%20(Linking)&rft.au=GALLET,%20Justine&LAURENT,%20Francois&PARIS,%20Christophe&CLIN,%20Benedicte&GISLARD,%20Antoine&rft.genre=article


Archivos en el ítem

ArchivosTamañoFormatoVer

No hay archivos asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem