Chromosomes synthétiques - Réécrire le code de la vie
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| dc.contributor.author | BABY, Vincent | |
| hal.structure.identifier | Universität Bern / University of Bern [UNIBE] | |
| dc.contributor.author | LABROUSSAA, Fabien | |
| hal.structure.identifier | Biologie du fruit et pathologie [BFP] | |
| dc.contributor.author | LARTIGUE, Carole | |
| hal.structure.identifier | Département de biologie [Sherbrooke] [UdeS] | |
| dc.contributor.author | RODRIGUE, Sebastien | |
| dc.date.issued | 2019 | |
| dc.identifier.issn | 0767-0974 | |
| dc.description.abstractEn | The past decade has seen vast improvements in DNA synthesis and assembly methods. The creation of synthetic DNA molecules is becoming easier and more affordable, such that entire chromosomes can now be synthesized. These advances mark the beginning of synthetic genomics, a new discipline interested in the construction of complete genomes tailored for the study and application of biological systems. From viral genome synthesis to the reconstruction of the yeast 16 chromosomes, we discuss the main discoveries, the regulations and ethical considerations along with the potential of this emerging discipline for the future. | |
| dc.language.iso | fr | |
| dc.publisher | EDP Sciences | |
| dc.title | Chromosomes synthétiques - Réécrire le code de la vie | |
| dc.title.en | Synthetic chromosomes: rewriting the code of life | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1051/medsci/2019153 | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Biologie animale | |
| bordeaux.journal | Médecine/Sciences | |
| bordeaux.page | 753-760 | |
| bordeaux.volume | 35 | |
| bordeaux.issue | 10 | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-02627953 | |
| hal.version | 1 | |
| hal.popular | non | |
| hal.audience | Nationale | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-02627953v1 | |
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