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Chromosomes synthétiques - Réécrire le code de la vie

hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorBABY, Vincent
hal.structure.identifierUniversität Bern / University of Bern [UNIBE]
dc.contributor.authorLABROUSSAA, Fabien
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorLARTIGUE, Carole
hal.structure.identifierDépartement de biologie [Sherbrooke] [UdeS]
dc.contributor.authorRODRIGUE, Sebastien
dc.date.issued2019
dc.identifier.issn0767-0974
dc.description.abstractEnThe past decade has seen vast improvements in DNA synthesis and assembly methods. The creation of synthetic DNA molecules is becoming easier and more affordable, such that entire chromosomes can now be synthesized. These advances mark the beginning of synthetic genomics, a new discipline interested in the construction of complete genomes tailored for the study and application of biological systems. From viral genome synthesis to the reconstruction of the yeast 16 chromosomes, we discuss the main discoveries, the regulations and ethical considerations along with the potential of this emerging discipline for the future.
dc.language.isofr
dc.publisherEDP Sciences
dc.titleChromosomes synthétiques - Réécrire le code de la vie
dc.title.enSynthetic chromosomes: rewriting the code of life
dc.typeArticle de revue
dc.identifier.doi10.1051/medsci/2019153
dc.subject.halSciences du Vivant [q-bio]/Biologie animale
bordeaux.journalMédecine/Sciences
bordeaux.page753-760
bordeaux.volume35
bordeaux.issue10
bordeaux.peerReviewedoui
hal.identifierhal-02627953
hal.version1
hal.popularnon
hal.audienceNationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-02627953v1
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