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Magnetic nanoparticle design for medical applications

hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorMORNET, Stéphane
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorVASSEUR, Sébastien
hal.structure.identifierInstitut des Sciences Chimiques de Rennes [ISCR]
dc.contributor.authorGRASSET, Fabien
hal.structure.identifierInstitute of Physics
dc.contributor.authorVEVERKA, P.
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorGOGLIO, Graziella
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorDEMOURGUES, Alain
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorPORTIER, Josik
hal.structure.identifierInstitute of Physics
dc.contributor.authorPOLLERT, E.
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorDUGUET, Etienne
dc.date.issued2006
dc.identifier.issn0079-6786
dc.description.abstractEnMagnetic nanoparticles have attracted attention because of their current and potential usefulness as contrast agents for magnetic resonance imaging (MRI) or colloidal mediators for cancer magnetic hyperthermia. This contribution examines these in vivo applications through an understanding of the involved problems and the current and future possibilities for resolving them. A special emphasis is made on magnetic nanoparticle requirements from a physical viewpoint (e.g. relaxivity for MRI and specific absorption rate for hyperthermia), the factors affecting their biodistribution and the solutions envisaged for enhancing their half-life in the blood compartment and targeting tumour cells. Then, the synthesis strategies developed in our group are presented and focused on covalent platforms capable to be tailor-derivatised by surface molecular chemistry. The opportunity of using more complex oxides than conventional magnetite for controlling the in vivo temperature is also discussed.
dc.language.isoen
dc.publisherElsevier
dc.subject.enMagnetic nanoparticles
dc.subject.enBiotechnology
dc.subject.enMedical applications
dc.subject.enNanomaterials
dc.subject.enBiomaterials
dc.typeArticle de revue
dc.identifier.doi10.1016/j.progsolidstchem.2005.11.010
dc.subject.halChimie/Matériaux
bordeaux.journalProgress in Solid State Chemistry
bordeaux.page237-247
bordeaux.volume34
bordeaux.issue2
bordeaux.peerReviewedoui
hal.identifierhal-00079998
hal.version1
hal.popularnon
hal.audienceInternationale
dc.title.itMagnetic nanoparticle design for medical applications
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00079998v1
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