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dc.rights.licenseopenen_US
hal.structure.identifierCentre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
dc.contributor.authorDOURNES, Gael
dc.contributor.authorWALKUP, Laura L.
hal.structure.identifierCentre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
dc.contributor.authorBENLALA, Ilyes
dc.contributor.authorWILLMERING, Matthew M.
hal.structure.identifierCentre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
dc.contributor.authorMACEY, Julie
dc.contributor.authorBUI, Stephanie
hal.structure.identifierCentre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] [CRCTB]
dc.contributor.authorLAURENT, Francois
dc.contributor.authorWOODS, Jason C.
dc.date.accessioned2022-10-11T14:07:23Z
dc.date.available2022-10-11T14:07:23Z
dc.date.issued2020-12-17
dc.identifier.issn0012-3692en_US
dc.identifier.urioai:crossref.org:10.1016/j.chest.2020.12.008
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/148382
dc.description.abstractEnTo assess airway and lung parenchymal damage noninvasively in cystic fibrosis (CF), chest MRI has been historically out of the scope of routine clinical imaging because of technical difficulties such as low proton density and respiratory and cardiac motion. However, technological breakthroughs have emerged that dramatically improve lung MRI quality (including signal-to-noise ratio, resolution, speed, and contrast). At the same time, novel treatments have changed the landscape of CF clinical care. In this contemporary context, there is now consensus that lung MRI can be used clinically to assess CF in a radiation-free manner and to enable quantification of lung disease severity. MRI can now achieve three-dimensional, high-resolution morphologic imaging, and beyond this morphologic information, MRI may offer the ability to sensitively differentiate active inflammation vs scarring tissue. MRI could also characterize various forms of inflammation for early guidance of treatment. Moreover, functional information from MRI can be used to assess regional, small-airway disease with sensitivity to detect small changes even in patients with mild CF. Finally, automated quantification methods have emerged to support conventional visual analyses for more objective and reproducible assessment of disease severity. This article aims to review the most recent developments of lung MRI, with a focus on practical application and clinical value in CF, and the perspectives on how these modern techniques may converge and impact patient care soon.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.sourcecrossref
dc.subject.enCystic fibrosis
dc.subject.enImaging
dc.subject.enLung
dc.subject.enMagnetic resonance
dc.title.enThe clinical use of lung MRI in cystic fibrosis: what, now, how?
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.chest.2020.12.008en_US
dc.subject.halSciences de l'ingénieur [physics]en_US
dc.identifier.pubmed33345950en_US
bordeaux.journalChesten_US
bordeaux.page2205-2217en_US
bordeaux.volume159en_US
bordeaux.hal.laboratoriesCentre de Recherche Cardio-Thoracique de Bordeaux (CRCTB) - U 1045en_US
bordeaux.issue6en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcedissemin
hal.identifierhal-03811036
hal.version1
hal.date.transferred2022-10-11T14:07:28Z
hal.exporttrue
workflow.import.sourcedissemin
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Chest&rft.date=2020-12-17&rft.volume=159&rft.issue=6&rft.spage=2205-2217&rft.epage=2205-2217&rft.eissn=0012-3692&rft.issn=0012-3692&rft.au=DOURNES,%20Gael&WALKUP,%20Laura%20L.&BENLALA,%20Ilyes&WILLMERING,%20Matthew%20M.&MACEY,%20Julie&rft.genre=article


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