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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorVIGNALS, Carole
dc.contributor.authorDICK, David W.
hal.structure.identifierStatistics In System biology and Translational Medicine [SISTM]
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorTHIEBAUT, Rodolphe
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorWITTKOP, Linda
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorPRAGUE, Melanie
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorHEFFERNAN, Jane M.
dc.date.accessioned2022-06-17T09:47:49Z
dc.date.available2022-06-17T09:47:49Z
dc.date.issued2021-10-09
dc.identifier.issn2673-8112en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/140264
dc.description.abstractEnNon-pharmaceutical interventions have been implemented intermittently for more than a year in most countries of the world to mitigate the COVID-19 epidemic. In France, while the vaccination campaign is progressing, the French government has decided to remove many public health restrictions such as business closure, lockdowns, and curfews. Nonetheless, social distancing, mask wearing, and hand washing (also called barrier gestures) are still recommended. We utilize an age-structured compartmental SEIR model that takes into account the SARS-CoV-2 waning immunity, vaccination, and increased transmissibility from variants of concern to estimate if barrier gestures can be relaxed without causing a resurgence of severe infections. This model assumes that the susceptibility to infection is a function of immunity status, which depends on initial infection severity and vaccination status. It is calibrated on confirmed COVID-19 cases from the French surveillance database, and accounts for changes in contact behaviors due to the implementation of nation-wide public health policies. We study the partial and full relaxation of barrier gestures occurring from August to December 2021 under various immunity duration assumptions. Maintaining the application of barrier gestures appears essential to avoid a resurgence of severe infections that would exceed French health care capacities, while surmounting vaccine hesitancy represents the key to consider their relaxation. Immunity duration assumptions significantly influence the short-term dynamic of the epidemic, which should be considered for further modelling.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enBooster campaign
dc.subject.enCOVID-19
dc.subject.enExit-strategy
dc.subject.enMathematical modelling
dc.subject.enSocial distancing
dc.subject.enWaning immunity
dc.title.enBarrier Gesture Relaxation during Vaccination Campaign in France: Modelling Impact of Waning Immunity
dc.typeArticle de revueen_US
dc.identifier.doi10.3390/covid1020041en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
bordeaux.journalCOVIDen_US
bordeaux.page472-488en_US
bordeaux.volume1en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue2en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamSISTM_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03375281
hal.version1
hal.exportfalse
dc.rights.ccCC BYen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=COVID&rft.date=2021-10-09&rft.volume=1&rft.issue=2&rft.spage=472-488&rft.epage=472-488&rft.eissn=2673-8112&rft.issn=2673-8112&rft.au=VIGNALS,%20Carole&DICK,%20David%20W.&THIEBAUT,%20Rodolphe&WITTKOP,%20Linda&PRAGUE,%20Melanie&rft.genre=article


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