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Association Between Adherence to Statins, Illness Perception, Treatment Satisfaction, and Quality of Life among Lebanese patients

dc.rights.licenseopenen_US
dc.contributor.authorHADDAD, C.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorHALLIT, Souheil
dc.contributor.authorSALHAB, M.
dc.contributor.authorHAJJ, A.
dc.contributor.authorSARKIS, A.
dc.contributor.authorAYOUB, E. N.
dc.contributor.authorJABBOUR, H.
dc.contributor.authorKHABBAZ, L. R.
dc.date.accessioned2020-11-16T09:33:05Z
dc.date.available2020-11-16T09:33:05Z
dc.date.issued2018-09
dc.identifier.issn1940-4034 (Electronic) 1074-2484 (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/14012
dc.description.abstractEnOBJECTIVES: The main objective of this study was to evaluate treatment adherence to statin and health-related quality of life (QOL) in Lebanese patients with dyslipidemia. Secondary objectives were to examine associations between treatment adherence, QOL, treatment satisfaction, and illness perception. METHODS: This cross-sectional study, conducted in 20 community pharmacies from all districts of Lebanon between August 2016 and April 2017, enrolled 247 adult patients taking any statin. RESULTS: The mean age of the participants was 52.63 +/- 11.92 years (57.5% males); the mean duration of treatment with a statin was 59.72 months. A significant association was found between adherence and marital status ( P < .0001), educational level ( P = .001), cigarette smoking ( P < .0001), and alcohol drinking ( P < .0001). A negative but significant correlation was found between the adherence score and the duration of dyslipidemia ( r = -0.199). A significant but negative correlation was also found between the side effect score and age ( r = -0.137). The monthly salary, the marital status, the educational level, smoking cigarettes or waterpipes, and drinking alcohol were all associated with the Illness Perception Questionnaire scores ( P < 0.0001 for all variables). Secondary level of education (beta = 13.43), smoking more than 3 waterpipes per week (beta = 14.06), global satisfaction score (beta = 0.32), convenience score (beta = 0.29), and effectiveness score (beta = 0.27) would significantly increase the adherence score. Smoking more than 15 cigarettes per day (beta = -11.15) and a divorced status (beta = -14.81) would however significantly decrease the adherence score. Significant associations were found between the illness perception score, the QOL domains, and the satisfaction domains ( P < .05 for all variables). CONCLUSION: This study showed that global satisfaction with treatment, convenience, and effectiveness are important factors that increase treatment adherence. Patient adherence results in patient satisfaction and improved QOL and is an important criterion for achieving desired therapeutic outcomes.
dc.language.isoENen_US
dc.subject.enEPICENE
dc.title.enAssociation Between Adherence to Statins, Illness Perception, Treatment Satisfaction, and Quality of Life among Lebanese patients
dc.title.alternativeJ Cardiovasc Pharmacol Theren_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1177/1074248418769635en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed29683005en_US
bordeaux.journalJournal of Cardiovascular Pharmacology and Therapeuticsen_US
bordeaux.page414-422en_US
bordeaux.volume23en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.issue5en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamEPICENEen_US
bordeaux.teamEPICENE_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03193821
hal.version1
hal.date.transferred2021-04-09T07:52:46Z
hal.exporttrue
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