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New insights into the genetic etiology of Alzheimer's disease and related dementias
dc.rights.license | open | en_US |
dc.contributor.author | BELLENGUEZ, Celine | |
dc.contributor.author | KUCUKALI, Fahri | |
dc.contributor.author | JANSEN, Iris E. | |
dc.contributor.author | KLEINEIDAM, Luca | |
dc.contributor.author | MORENO-GRAU, Sonia | |
dc.contributor.author | AMIN, Najaf | |
dc.contributor.author | NAJ, Adam C. | |
dc.contributor.author | CAMPOS-MARTIN, Rafael | |
dc.contributor.author | GRENIER-BOLEY, Benjamin | |
dc.contributor.author | ANDRADE, Victor | |
dc.contributor.author | HOLMANS, Peter A. | |
dc.contributor.author | BOLAND, Anne | |
dc.contributor.author | DAMOTTE, Vincent | |
dc.contributor.author | VAN DER LEE, Sven J. | |
dc.contributor.author | COSTA, Marcos R. | |
dc.contributor.author | KUULASMAA, Teemu | |
dc.contributor.author | YANG, Qiong | |
dc.contributor.author | DE ROJAS, Itziar | |
dc.contributor.author | BIS, Joshua C. | |
dc.contributor.author | YAQUB, Amber | |
dc.contributor.author | PROKIC, Ivana | |
dc.contributor.author | CHAPUIS, Julien | |
dc.contributor.author | AHMAD, Shahzad | |
dc.contributor.author | GIEDRAITIS, Vilmantas | |
dc.contributor.author | AARSLAND, Dag | |
dc.contributor.author | GARCIA-GONZALEZ, Pablo | |
dc.contributor.author | ABDELNOUR, Carla | |
dc.contributor.author | ALARCON-MARTIN, Emilio | |
dc.contributor.author | ALCOLEA, Daniel | |
dc.contributor.author | ALEGRET, Montserrat | |
dc.contributor.author | ALVAREZ, Ignacio | |
dc.contributor.author | ALVAREZ, Victoria | |
dc.contributor.author | ARMSTRONG, Nicola J. | |
dc.contributor.author | TSOLAKI, Anthoula | |
dc.contributor.author | ANTUNEZ, Carmen | |
dc.contributor.author | APPOLLONIO, Ildebrando | |
dc.contributor.author | ARCARO, Marina | |
dc.contributor.author | ARCHETTI, Silvana | |
dc.contributor.author | PASTOR, Alfonso Arias | |
dc.contributor.author | AROSIO, Beatrice | |
dc.contributor.author | ATHANASIU, Lavinia | |
dc.contributor.author | BAILLY, Henri | |
dc.contributor.author | BANAJ, Nerisa | |
dc.contributor.author | BAQUERO, Miquel | |
dc.contributor.author | BARRAL, Sandra | |
dc.contributor.author | BEISER, Alexa | |
dc.contributor.author | PASTOR, Ana Belen | |
dc.contributor.author | BELOW, Jennifer E. | |
dc.contributor.author | BENCHEK, Penelope | |
dc.contributor.author | BENUSSI, Luisa | |
dc.contributor.author | BERR, Claudine | |
dc.contributor.author | BESSE, Celine | |
dc.contributor.author | BESSI, Valentina | |
dc.contributor.author | BINETTI, Giuliano | |
dc.contributor.author | BIZARRO, Alessandra | |
dc.contributor.author | BLESA, Rafael | |
dc.contributor.author | BOADA, Merce | |
dc.contributor.author | BOERWINKLE, Eric | |
dc.contributor.author | BORRONI, Barbara | |
dc.contributor.author | BOSCHI, Silvia | |
dc.contributor.author | BOSSU, Paola | |
dc.contributor.author | BRATHEN, Geir | |
dc.contributor.author | BRESSLER, Jan | |
dc.contributor.author | BRESNER, Catherine | |
dc.contributor.author | BRODATY, Henry | |
dc.contributor.author | BROOKES, Keeley J. | |
dc.contributor.author | BRUSCO, Luis Ignacio | |
dc.contributor.author | BUIZA-RUEDA, Dolores | |
dc.contributor.author | BURGER, Katharina | |
dc.contributor.author | BURHOLT, Vanessa | |
dc.contributor.author | BUSH, William S. | |
dc.contributor.author | CALERO, Miguel | |
dc.contributor.author | CANTWELL, Laura B. | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | CHENE, Genevieve | |
dc.contributor.author | CHUNG, Jaeyoon | |
dc.contributor.author | CUCCARO, Michael L. | |
dc.contributor.author | CARRACEDO, Angel | |
dc.contributor.author | CECCHETTI, Roberta | |
dc.contributor.author | CERVERA-CARLES, Laura | |
dc.contributor.author | CHARBONNIER, Camille | |
dc.contributor.author | CHEN, Hung-Hsin | |
dc.contributor.author | CHILLOTTI, Caterina | |
dc.contributor.author | CICCONE, Simona | |
dc.contributor.author | CLAASSEN, Jurgen A. H. R. | |
dc.contributor.author | CLARK, Christopher | |
dc.contributor.author | CONTI, Elisa | |
dc.contributor.author | CORMA-GOMEZ, Anais | |
dc.contributor.author | COSTANTINI, Emanuele | |
dc.contributor.author | CUSTODERO, Carlo | |
dc.contributor.author | DAIAN, Delphine | |
dc.contributor.author | DALMASSO, Maria Carolina | |
dc.contributor.author | DANIELE, Antonio | |
dc.contributor.author | DARDIOTIS, Efthimios | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | DARTIGUES, Jean-Francois | |
dc.contributor.author | DE DEYN, Peter Paul | |
dc.contributor.author | DE PAIVA LOPES, Katia | |
dc.contributor.author | DE WITTE, Lot D. | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | DEBETTE, Stephanie | |
dc.contributor.author | DECKERT, Jurgen | |
dc.contributor.author | DEL SER, Teodoro | |
dc.contributor.author | DENNING, Nicola | |
dc.contributor.author | DESTEFANO, Anita | |
dc.contributor.author | DICHGANS, Martin | |
dc.contributor.author | DIEHL-SCHMID, Janine | |
dc.contributor.author | DIEZ-FAIREN, Monica | |
dc.contributor.author | ROSSI, Paolo Dionigi | |
dc.contributor.author | DJUROVIC, Srdjan | |
dc.contributor.author | DURON, Emmanuelle | |
dc.contributor.author | DUZEL, Emrah | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | DUFOUIL, Carole | |
dc.contributor.author | EIRIKSDOTTIR, Gudny | |
dc.contributor.author | ENGELBORGHS, Sebastiaan | |
dc.contributor.author | ESCOTT-PRICE, Valentina | |
dc.contributor.author | ESPINOSA, Ana | |
dc.contributor.author | EWERS, Michael | |
dc.contributor.author | FABER, Kelley M. | |
dc.contributor.author | FABRIZIO, Tagliavini | |
dc.contributor.author | NIELSEN, Sune Fallgaard | |
dc.contributor.author | FARDO, David W. | |
dc.contributor.author | FAROTTI, Lucia | |
dc.contributor.author | FENOGLIO, Chiara | |
dc.contributor.author | FERNANDEZ-FUERTES, Marta | |
dc.contributor.author | FERRARI, Raffaele | |
dc.contributor.author | FERREIRA, Catarina B. | |
dc.contributor.author | FERRI, Evelyn | |
dc.contributor.author | FIN, Bertrand | |
dc.contributor.author | FISCHER, Peter | |
dc.contributor.author | FLADBY, Tormod | |
dc.contributor.author | FLIESSBACH, Klaus | |
dc.contributor.author | FONGANG, Bernard | |
dc.contributor.author | FORNAGE, Myriam | |
dc.contributor.author | FORTEA, Juan | |
dc.contributor.author | FOROUD, Tatiana M. | |
dc.contributor.author | FOSTINELLI, Silvia | |
dc.contributor.author | FOX, Nick C. | |
dc.contributor.author | FRANCO-MACIAS, Emlio | |
dc.contributor.author | BULLIDO, Maria J. | |
dc.contributor.author | FRANK-GARCIA, Ana | |
dc.contributor.author | FROELICH, Lutz | |
dc.contributor.author | FULTON-HOWARD, Brian | |
dc.contributor.author | GALIMBERTI, Daniela | |
dc.contributor.author | GARCIA-ALBERCA, Jose Maria | |
dc.contributor.author | GARCIA-MADRONA, Sebastian | |
dc.contributor.author | GARCIA-RIBAS, Guillermo | |
dc.contributor.author | GHIDONI, Roberta | |
dc.contributor.author | GIEGLING, Ina | |
dc.contributor.author | GIORGIO, Giaccone | |
dc.contributor.author | GOATE, Alison M. | |
dc.contributor.author | GOLDHARDT, Oliver | |
dc.contributor.author | GOMEZ-FONSECA, Duber | |
dc.contributor.author | GONZALEZ-PEREZ, Antonio | |
dc.contributor.author | GRAFF, Caroline | |
dc.contributor.author | GRANDE, Giulia | |
dc.contributor.author | GREEN, Emma | |
dc.contributor.author | GRIMMER, Timo | |
dc.contributor.author | GRUNBLATT, Edna | |
dc.contributor.author | GRUNIN, Michelle | |
dc.contributor.author | GUDNASON, Vilmundur | |
dc.contributor.author | GUETTA-BARANES, Tamar | |
dc.contributor.author | HAAPASALO, Annakaisa | |
dc.contributor.author | HADJIGEORGIOU, Georgios | |
dc.contributor.author | HAINES, Jonathan L. | |
dc.contributor.author | HAMILTON-NELSON, Kara L. | |
dc.contributor.author | HAMPEL, Harald | |
dc.contributor.author | HANON, Olivier | |
dc.contributor.author | HARDY, John | |
dc.contributor.author | HARTMANN, Annette M. | |
dc.contributor.author | HAUSNER, Lucrezia | |
dc.contributor.author | HARWOOD, Janet | |
dc.contributor.author | HEILMANN-HEIMBACH, Stefanie | |
dc.contributor.author | HELISALMI, Seppo | |
dc.contributor.author | HENEKA, Michael T. | |
dc.contributor.author | HERNANDEZ, Isabel | |
dc.contributor.author | HERRMANN, Martin J. | |
dc.contributor.author | HOFFMANN, Per | |
dc.contributor.author | HOLMES, Clive | |
dc.contributor.author | HOLSTEGE, Henne | |
dc.contributor.author | VILAS, Raquel Huerto | |
dc.contributor.author | HULSMAN, Marc | |
dc.contributor.author | HUMPHREY, Jack | |
dc.contributor.author | BIESSELS, Geert Jan | |
dc.contributor.author | JIAN, Xueqiu | |
dc.contributor.author | JOHANSSON, Charlotte | |
dc.contributor.author | JUN, Gyungah R. | |
dc.contributor.author | KASTUMATA, Yuriko | |
dc.contributor.author | KAUWE, John | |
dc.contributor.author | KEHOE, Patrick G. | |
dc.contributor.author | KILANDER, Lena | |
dc.contributor.author | STAHLBOM, Anne Kinhult | |
dc.contributor.author | KIVIPELTO, Miia | |
dc.contributor.author | KOIVISTO, Anne | |
dc.contributor.author | KORNHUBER, Johannes | |
dc.contributor.author | KOSMIDIS, Mary H. | |
dc.contributor.author | KUKULL, Walter A. | |
dc.contributor.author | KUKSA, Pavel P. | |
dc.contributor.author | KUNKLE, Brian W. | |
dc.contributor.author | KUZMA, Amanda B. | |
dc.contributor.author | LAGE, Carmen | |
dc.contributor.author | LAUKKA, Erika J. | |
dc.contributor.author | LAUNER, Lenore | |
dc.contributor.author | LAURIA, Alessandra | |
dc.contributor.author | LEE, Chien-Yueh | |
dc.contributor.author | LEHTISALO, Jenni | |
dc.contributor.author | LERCH, Ondrej | |
dc.contributor.author | LLEO, Alberto | |
dc.contributor.author | LONGSTRETH, William Jr | |
dc.contributor.author | LOPEZ, Oscar | |
dc.contributor.author | DE MUNAIN, Adolfo Lopez | |
dc.contributor.author | LOVE, Seth | |
dc.contributor.author | LOWEMARK, Malin | |
dc.contributor.author | LUCKCUCK, Lauren | |
dc.contributor.author | LUNETTA, Kathryn L. | |
dc.contributor.author | MA, Yiyi | |
dc.contributor.author | MACIAS, Juan | |
dc.contributor.author | MACLEOD, Catherine A. | |
dc.contributor.author | MAIER, Wolfgang | |
dc.contributor.author | MANGIALASCHE, Francesca | |
dc.contributor.author | SPALLAZZI, Marco | |
dc.contributor.author | MARQUIE, Marta | |
dc.contributor.author | MARSHALL, Rachel | |
dc.contributor.author | MARTIN, Eden R. | |
dc.contributor.author | MONTES, Angel Martin | |
dc.contributor.author | RODRIGUEZ, Carmen Martinez | |
dc.contributor.author | MASULLO, Carlo | |
dc.contributor.author | MAYEUX, Richard | |
dc.contributor.author | MEAD, Simon | |
dc.contributor.author | MECOCCI, Patrizia | |
dc.contributor.author | MEDINA, Miguel | |
dc.contributor.author | MEGGY, Alun | |
dc.contributor.author | MEHRABIAN, Shima | |
dc.contributor.author | MENDOZA, Silvia | |
dc.contributor.author | MENENDEZ-GONZALEZ, Manuel | |
dc.contributor.author | MIR, Pablo | |
dc.contributor.author | MOEBUS, Susanne | |
dc.contributor.author | MOL, Merel | |
dc.contributor.author | MOLINA-PORCEL, Laura | |
dc.contributor.author | MONTRREAL, Laura | |
dc.contributor.author | MORELLI, Laura | |
dc.contributor.author | MORENO, Fermin | |
dc.contributor.author | MORGAN, Kevin | |
dc.contributor.author | MOSLEY, Thomas | |
dc.contributor.author | NOTHEN, Markus M. | |
dc.contributor.author | MUCHNIK, Carolina | |
dc.contributor.author | MUKHERJEE, Shubhabrata | |
dc.contributor.author | NACMIAS, Benedetta | |
dc.contributor.author | NGANDU, Tiia | |
dc.contributor.author | NICOLAS, Gael | |
dc.contributor.author | NORDESTGAARD, Borge G. | |
dc.contributor.author | OLASO, Robert | |
dc.contributor.author | ORELLANA, Adelina | |
dc.contributor.author | ORSINI, Michela | |
dc.contributor.author | ORTEGA, Gemma | |
dc.contributor.author | PADOVANI, Alessandro | |
dc.contributor.author | PAOLO, Caffarra | |
dc.contributor.author | PAPENBERG, Goran | |
dc.contributor.author | PARNETTI, Lucilla | |
dc.contributor.author | PASQUIER, Florence | |
dc.contributor.author | PASTOR, Pau | |
dc.contributor.author | PELOSO, Gina | |
dc.contributor.author | PEREZ-CORDON, Alba | |
dc.contributor.author | PEREZ-TUR, Jordi | |
dc.contributor.author | PERICARD, Pierre | |
dc.contributor.author | PETERS, Oliver | |
dc.contributor.author | PIJNENBURG, Yolande A. L. | |
dc.contributor.author | PINEDA, Juan A. | |
dc.contributor.author | PINOL-RIPOLL, Gerard | |
dc.contributor.author | PISANU, Claudia | |
dc.contributor.author | POLAK, Thomas | |
dc.contributor.author | POPP, Julius | |
dc.contributor.author | POSTHUMA, Danielle | |
dc.contributor.author | PRILLER, Josef | |
dc.contributor.author | PUERTA, Raquel | |
dc.contributor.author | QUENEZ, Olivier | |
dc.contributor.author | QUINTELA, Ines | |
dc.contributor.author | THOMASSEN, Jesper Qvist | |
dc.contributor.author | RABANO, Alberto | |
dc.contributor.author | RAINERO, Innocenzo | |
dc.contributor.author | RAJABLI, Farid | |
dc.contributor.author | RAMAKERS, Inez | |
dc.contributor.author | REAL, Luis M. | |
dc.contributor.author | REINDERS, Marcel J. T. | |
dc.contributor.author | REITZ, Christiane | |
dc.contributor.author | REYES-DUMEYER, Dolly | |
dc.contributor.author | RIDGE, Perry | |
dc.contributor.author | RIEDEL-HELLER, Steffi | |
dc.contributor.author | RIEDERER, Peter | |
dc.contributor.author | ROBERTO, Natalia | |
dc.contributor.author | RODRIGUEZ-RODRIGUEZ, Eloy | |
dc.contributor.author | RONGVE, Arvid | |
dc.contributor.author | ALLENDE, Irene Rosas | |
dc.contributor.author | ROSENDE-ROCA, Maitee | |
dc.contributor.author | ROYO, Jose Luis | |
dc.contributor.author | RUBINO, Elisa | |
dc.contributor.author | RUJESCU, Dan | |
dc.contributor.author | SAEZ, Maria Eugenia | |
dc.contributor.author | SAKKA, Paraskevi | |
dc.contributor.author | SALTVEDT, Ingvild | |
dc.contributor.author | SANABRIA, Angela | |
dc.contributor.author | SANCHEZ-ARJONA, Maria Bernal | |
dc.contributor.author | SANCHEZ-GARCIA, Florentino | |
dc.contributor.author | JUAN, Pascual Sanchez | |
dc.contributor.author | SANCHEZ-VALLE, Raquel | |
dc.contributor.author | SANDO, Sigrid B. | |
dc.contributor.author | SARNOWSKI, Chloe | |
dc.contributor.author | SATIZABAL, Claudia L. | |
dc.contributor.author | SCAMOSCI, Michela | |
dc.contributor.author | SCARMEAS, Nikolaos | |
dc.contributor.author | SCARPINI, Elio | |
dc.contributor.author | SCHELTENS, Philip | |
dc.contributor.author | SCHERBAUM, Norbert | |
dc.contributor.author | SCHERER, Martin | |
dc.contributor.author | SCHMID, Matthias | |
dc.contributor.author | SCHNEIDER, Anja | |
dc.contributor.author | SCHOTT, Jonathan M. | |
dc.contributor.author | SELBAEK, Geir | |
dc.contributor.author | SERIPA, Davide | |
dc.contributor.author | SERRANO, Manuel | |
dc.contributor.author | SHA, Jin | |
dc.contributor.author | SHADRIN, Alexey A. | |
dc.contributor.author | SKROBOT, Olivia | |
dc.contributor.author | SLIFER, Susan | |
dc.contributor.author | SNIJDERS, Gijsje J. L. | |
dc.contributor.author | SOININEN, Hilkka | |
dc.contributor.author | SOLFRIZZI, Vincenzo | |
dc.contributor.author | SOLOMON, Alina | |
dc.contributor.author | SONG, Yeunjoo | |
dc.contributor.author | SORBI, Sandro | |
dc.contributor.author | SOTOLONGO-GRAU, Oscar | |
dc.contributor.author | SPALLETTA, Gianfranco | |
dc.contributor.author | SPOTTKE, Annika | |
dc.contributor.author | SQUASSINA, Alessio | |
dc.contributor.author | STORDAL, Eystein | |
dc.contributor.author | TARTAN, Juan Pablo | |
dc.contributor.author | TARRAGA, Lluis | |
dc.contributor.author | TESI, Niccolo | |
dc.contributor.author | THALAMUTHU, Anbupalam | |
dc.contributor.author | THOMAS, Tegos | |
dc.contributor.author | TOSTO, Giuseppe | |
dc.contributor.author | TRAYKOV, Latchezar | |
dc.contributor.author | TREMOLIZZO, Lucio | |
dc.contributor.author | TYBJAERG-HANSEN, Anne | |
dc.contributor.author | UITTERLINDEN, Andre | |
dc.contributor.author | ULLGREN, Abbe | |
dc.contributor.author | ULSTEIN, Ingun | |
dc.contributor.author | VALERO, Sergi | |
dc.contributor.author | VALLADARES, Otto | |
dc.contributor.author | BROECKHOVEN, Christine Van | |
dc.contributor.author | VANCE, Jeffery | |
dc.contributor.author | VARDARAJAN, Badri N. | |
dc.contributor.author | VAN DER LUGT, Aad | |
dc.contributor.author | DONGEN, Jasper Van | |
dc.contributor.author | VAN ROOIJ, Jeroen | |
dc.contributor.author | VAN SWIETEN, John | |
dc.contributor.author | VANDENBERGHE, Rik | |
dc.contributor.author | VERHEY, Frans | |
dc.contributor.author | VIDAL, Jean-Sebastien | |
dc.contributor.author | VOGELGSANG, Jonathan | |
dc.contributor.author | VYHNALEK, Martin | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | WAGNER, Michael | |
dc.contributor.author | WALLON, David | |
dc.contributor.author | WANG, Li-San | |
dc.contributor.author | WANG, Ruiqi | |
dc.contributor.author | WEINHOLD, Leonie | |
dc.contributor.author | WILTFANG, Jens | |
dc.contributor.author | WINDLE, Gill | |
dc.contributor.author | WOODS, Bob | |
dc.contributor.author | YANNAKOULIA, Mary | |
dc.contributor.author | ZARE, Habil | |
dc.contributor.author | ZHAO, Yi | |
dc.contributor.author | ZHANG, Xiaoling | |
dc.contributor.author | ZHU, Congcong | |
dc.contributor.author | ZULAICA, Miren | |
dc.contributor.author | FARRER, Lindsay A. | |
dc.contributor.author | PSATY, Bruce M. | |
dc.contributor.author | GHANBARI, Mohsen | |
dc.contributor.author | RAJ, Towfique | |
dc.contributor.author | SACHDEV, Perminder | |
dc.contributor.author | MATHER, Karen | |
dc.contributor.author | JESSEN, Frank | |
dc.contributor.author | IKRAM, M. Arfan | |
dc.contributor.author | DE MENDONCA, Alexandre | |
dc.contributor.author | HORT, Jakub | |
dc.contributor.author | TSOLAKI, Magda | |
dc.contributor.author | PERICAK-VANCE, Margaret A. | |
dc.contributor.author | AMOUYEL, Philippe | |
dc.contributor.author | WILLIAMS, Julie | |
dc.contributor.author | FRIKKE-SCHMIDT, Ruth | |
dc.contributor.author | CLARIMON, Jordi | |
dc.contributor.author | DELEUZE, Jean-Francois | |
dc.contributor.author | ROSSI, Giacomina | |
dc.contributor.author | SESHADRI, Sudha | |
dc.contributor.author | ANDREASSEN, Ole A. | |
dc.contributor.author | INGELSSON, Martin | |
dc.contributor.author | HILTUNEN, Mikko | |
dc.contributor.author | SLEEGERS, Kristel | |
dc.contributor.author | SCHELLENBERG, Gerard D. | |
dc.contributor.author | VAN DUIJN, Cornelia M. | |
dc.contributor.author | SIMS, Rebecca | |
dc.contributor.author | VAN DER FLIER, Wiesje M. | |
dc.contributor.author | RUIZ, Agustin | |
dc.contributor.author | RAMIREZ, Alfredo | |
dc.contributor.author | LAMBERT, Jean-Charles | |
dc.date.accessioned | 2022-05-16T09:23:55Z | |
dc.date.available | 2022-05-16T09:23:55Z | |
dc.date.issued | 2022-04-04 | |
dc.identifier.issn | 1546-1718 (Electronic) 1061-4036 (Linking) | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/140064 | |
dc.description.abstractEn | Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele. | |
dc.language.iso | EN | en_US |
dc.rights | Attribution 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
dc.title.en | New insights into the genetic etiology of Alzheimer's disease and related dementias | |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1038/s41588-022-01024-z | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
dc.identifier.pubmed | 35379992 | en_US |
bordeaux.journal | Nature Genetics | en_US |
bordeaux.page | 412-436 | en_US |
bordeaux.volume | 54 | en_US |
bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
bordeaux.issue | 4 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | INSERM | en_US |
bordeaux.team | ACTIVE_BPH | en_US |
bordeaux.team | BIOSTAT_BPH | en_US |
bordeaux.team | ELEANOR_BPH | en_US |
bordeaux.team | PHARES_BPH | en_US |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
bordeaux.identifier.funderID | Institut National de la Santé et de la Recherche Médicale | en_US |
bordeaux.identifier.funderID | Institute Pasteur De Lille | en_US |
hal.identifier | hal-03668928 | |
hal.version | 1 | |
hal.date.transferred | 2022-05-16T09:24:26Z | |
hal.export | true | |
dc.rights.cc | Pas de Licence CC | en_US |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nature%20Genetics&rft.date=2022-04-04&rft.volume=54&rft.issue=4&rft.spage=412-436&rft.epage=412-436&rft.eissn=1546-1718%20(Electronic)%201061-4036%20(Linking)&rft.issn=1546-1718%20(Electronic)%201061-4036%20(Linking)&rft.au=BELLENGUEZ,%20Celine&KUCUKALI,%20Fahri&JANSEN,%20Iris%20E.&KLEINEIDAM,%20Luca&MORENO-GRAU,%20Sonia&rft.genre=article |